2,2,3-Trimethyl-3-(2,2,2-trifluoroacetamido)butanoic acid CAS 1490961-27-7
| CAS No. | 1490961-27-7 |
| Molecular Formula | C9H14F3NO3 |
| Molecular Weight | 241.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,3-Trimethyl-3-(2,2,2-trifluoroacetamido)butanoic acid.
2,2,3-Trimethyl-3-(2,2,2-trifluoroacetamido)butanoic acid (CAS 1490961-27-7), molecular formula C9H14F3NO3 and molecular weight 241.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,2,3-Trimethyl-3-(2,2,2-trifluoroacetamido)butanoic acid (C9H14F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2,3-Trimethyl-3-(2,2,2-trifluoroacetamido)butanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14F3NO3 |
| Molecular Weight | 241.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trimethyl Standards
- 2,2,4-Trimethyl-7-(trifluoromethyl)-1,2-dihydroquinoline (CAS 1242835-50-2)
- 2,2,6-Trimethyl-2H-pyrano[3,2-c]quinolin-5(6H)-one (CAS 50333-13-6)
- 2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)-1,3-thiazolidine-4-carboxylic acid (CAS 1218739-03-7)
- 2,4,6-Trimethyl-n-propylbenzene-1-sulfonamide (CAS 189341-65-9)
- N-(4,4,6-Trimethyl-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)butyramide (CAS 58553-11-0)
- 1,1,1-Trimethyl-N,N-diphenylsilanamine (CAS 17425-91-1)
- Trimethyl(3-pyridyl)tin (CAS 59020-09-6)
- Trimethyl(4-pyridyl)tin (CAS 59020-06-3)
Recommended Standards
- ethyl 3-(N-ethyl-2,2,2-trifluoroacetamido)propanoate (CAS 1461708-71-3)
- 1-[4-(Trifluoromethoxy)phenyl]cyclobutanecarbonitrile (CAS 151157-62-9)
- [1-phenyl-5-(trifluoromethyl)-1h-pyrazol-4-yl]methanamine (CAS 1461707-98-1)
- (5E)-5-[(2,4-Difluorophenyl)methylidene]-1,3-thiazolidine-2,4-dione (CAS 153709-95-6)
- N-(3-Methylisothiazol-5-yl)benzofuran-2-carboxamide (CAS 1207002-91-2)
- 4-Pentylphenyl 4-(trans-4-butylcyclohexyl)benzoate (CAS 90937-41-0)
- N1,N2-bis(trimethylsilyl)ethane-1,2-diamine (CAS 1821-99-4)
- 3-Chloro-4-fluorophenethyl ethyl oxalate (CAS 1443309-36-1)
- p-(Benzoylamino)benzoic Acid (CAS 582-80-9)
- Acetophenone impurity 14 (CAS CATO-C4X-260814)
- 4-Formyl-N-(2-isopropoxyethyl)benzamide (CAS 1061567-05-2)
- 2-(3,4-Dimethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-17-0)
- 4-Methoxy-N-(4-nitrophenyl)benzamide (CAS 7464-52-0)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com