1-(4-Methoxy-3-(trifluoromethyl)phenyl)ethanone CAS 149105-10-2
| CAS No. | 149105-10-2 |
| Molecular Formula | C10H9F3O2 |
| Molecular Weight | 218.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-Methoxy-3-(trifluoromethyl)phenyl)ethanone (C10H9F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(4-Methoxy-3-(trifluoromethyl)phenyl)ethanone (CAS 149105-10-2) is a high-purity analytical reference standard with the molecular formula C10H9F3O2 and a molecular weight of 218.17 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O2 |
| Molecular Weight | 218.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Methoxy Standards
- 2-Methoxy-1-(2-(trifluoromethyl)phenyl)ethanone (CAS 1342027-89-7)
- 4-Methoxy-3-methyl-5-(trifluoromethyl)benzaldehyde (CAS 1431329-77-9)
- 2-Methoxy-5-methyl-2,2,2-trifluoroacetophenone (CAS 180311-39-1)
- 2-methoxy-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 192225-35-7)
- 1-(3-Methoxy-5-(trifluoromethyl)phenyl)ethan-1-one (CAS 916421-06-2)
- 1-(4-Methoxy-2-(trifluoromethyl)phenyl)ethanone (CAS 220141-75-3)
- 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 26771-69-7)
- 2-Methoxy-6-methyl-4-(trifluoromethyl)benzaldehyde (CAS 2090792-58-6)
Recommended Standards
- 3,4,5-Trifluorophenethyl acetate (CAS 1443351-10-7)
- 4,4,4-Trifluoro-3-phenylbutanoic acid (CAS 149680-95-5)
- (R)-2-(4-(Trifluoromethyl)phenyl)propanoic acid (CAS 150360-27-3)
- 2-(3,3,3-Trifluoropropyl)benzoic acid (CAS 1424445-88-4)
- 1-Iodo-3-(trimethoxymethyl)benzene (CAS 72525-29-2)
- 9-(4-Chlorophenyl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine (CAS 338773-24-3)
- N-Cyclohexyl-N-methyl-3-piperidinaminedihydrochloride (CAS 1220017-41-3)
- (E)-2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}-N-(4-methylphenyl)ethene-1-sulfonamide (CAS 478080-66-9)
- 5-(2-Chloro-4-(methylthio)phenyl)-5-oxovaleric acid (CAS 951889-90-0)
- Ethyl 4-(4-fluorophenyl)-4-oxobutanoate (CAS 41310-80-9)
- Ethyl 2-ethyl-2-(methylamino)butanoate (CAS 1183558-48-6)
- tert-Butyl 2-(2,4-dichlorobenzyl)piperazine-1-carboxylate (CAS 886776-19-8)
- tert-Butyl 2-cyano-2-(quinolin-2(1H)-ylidene)acetate (CAS 2859-27-0)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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