Gemfibrozil EP Impurity I CAS 149105-25-9
| CAS No. | 149105-25-9 |
| Molecular Formula | C16H24O3 |
| Molecular Weight | 264.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Gemfibrozil EP Impurity I (CAS 149105-25-9), a pharmacopoeial impurity reference standard (molecular formula C16H24O3, MW 264.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Gemfibrozil EP Impurity I (C16H24O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H24O3 |
| Molecular Weight | 264.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
Related Gemfibrozil Standards
- Gemfibrozil-d6 (2?2-dimethyl-d6) (CAS 1184986-45-5)
- Gemfibrozil Impurity N1 (CAS 63258-18-4)
- Iso-Gemfibrozil (CAS 86837-66-3)
- Gemfibrozil (CAS 25812-30-0)
- Gemfibrozil EP Impurity H (CAS 415724-02-6)
- Gemfibrozil Related Compound 16 (6-Propenyl Gemfibrozil) (Mixture of Z and E Isomers) (CAS 1798429-95-4)
- Gemfibrozil EP Impurity E (CAS 500904-61-0)
- Gemfibrozil Isopropyl Ester (CAS 154021-24-6)
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- (S)-Methyl 2-(2-chlorophenyl)-2-((2-(3-formylthiophen-2-yl)ethyl)(nitroso)amino)acetate (CAS CATO-C3D-26208)
- Ethyl (2-(3-ethyl-7-oxo-3,7-dihydro-6H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl)acetyl)glycinate (CAS 1058197-49-1)
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