Suvorexant Impurity 17 CAS 1293285-66-1
| CAS No. | 1293285-66-1 |
| Molecular Formula | C10H9N3O2 |
| Molecular Weight | 203.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Suvorexant Impurity 17 (CAS 1293285-66-1, C10H9N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Suvorexant Impurity 17 (C10H9N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Suvorexant Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9N3O2 |
| Molecular Weight | 203.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Suvorexant Standards
- Suvorexant intermediate II (CAS 956317-36-5)
- Suvorexant Impurity 13 (CAS 1149352-55-5)
- Suvorexant Impurity 16 (CAS 1824534-79-3)
- Suvorexant Impurity 18 (CAS 1785606-18-9)
- Suvorexant Impurity 39 (CAS 1293284-56-6)
- Suvorexant Impurity 32 (CAS 32850-82-1)
- Suvorexant Impurity 9 (CAS 2762965-06-8)
- Suvorexant Impurity 2 (CAS 1260619-38-2)
Recommended Standards
- Teneligliptin Impurity 59 (CAS CATO-C4X-176059)
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- Alanyl Glutamine Impurity 45 (CAS CATO-C4X-197445)
- Resmetirom impurity 108 (CAS CATO-C4X-2912108)
- Tofacitinib Impurity 63 (CAS 1354469-76-3)
- Pyridostigmine Impurity 5 (CAS CATO-C4X-26305)
- Prucalopride Impurity 35 (CAS 1098624-57-7)
- 4-Bromo-1-(phenoxymethyl)-1H-pyrazole (CAS 1263210-93-0)
- tert-Butyl 1-(3-chlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-13-8)
- N-(4-Piperidinyl)tetrahydro-2H-pyran-4-carboxamide hydrochloride (CAS 1220031-94-6)
- 4-(Tetrahydro-2h-pyran-3-yl)butan-2-one (CAS 1493074-87-5)
- Methyl 6-(3,4-dimethoxyphenyl)-2-formylnicotinate (CAS 244139-13-7)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
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