Gimeracil impurity 11 CAS 149143-67-9
| CAS No. | 149143-67-9 |
| Molecular Formula | C6H5ClN2O3 |
| Molecular Weight | 188.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 188.57 g/mol gives Gimeracil impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gimeracil impurity 11 (CAS 149143-67-9), a pharmacopoeial impurity reference standard (molecular formula C6H5ClN2O3, MW 188.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Gimeracil impurity 11 (C6H5ClN2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 188.57 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5ClN2O3 |
| Molecular Weight | 188.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Gimeracil Standards
Recommended Standards
- Amiloride Hydrochloride Dihydrate EP Impurity B (CAS 4878-36-8)
- 2-Chloro-5-methyl-4-nitropyridine 1-oxide (CAS 60323-96-8)
- (3-Chloro-6-oxopyridazin-1(6H)-yl)acetic acid 2-(3-chloro-6-oxopyridazin-1(6H)-yl)acetic acid 89581-61-3 (CAS 89581-61-3)
- 2-Amino-6-chloro-4-nitrophenol (CAS 6358-09-4)
- Roxadustat Impurity 177 (CAS CATO-C4X-2213177)
- Sitagliptin Impurity 77 (CAS 1152439-73-0)
- Flupentixol Impurity 19 (CAS CATO-C4X-189519)
- Benserazide Impurity 53 (CAS 773868-38-5)
- 5-(Bromomethyl)-2-methoxypyridine hydrobromide (CAS 1588441-28-4)
- 4-Ethoxy-2,6,7-trimethyl-1,2,3,4-tetrahydroquinoline (CAS 503438-75-3)
- 4-Oxo-4-((4-propoxyphenyl)amino)butanoic acid (CAS 881228-60-0)
- Allyl(3-chlorophenyl)sulfane (CAS 477983-30-5)
- 7-(2,5-Dimethoxyphenyl)-7-oxoheptanoic acid (CAS 898792-41-1)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com