Arbidol Impurity 46 CAS 149246-36-6
| CAS No. | 149246-36-6 |
| Molecular Formula | C13H13Br2NO3 |
| Molecular Weight | 391.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Arbidol Impurity 46 (CAS 149246-36-6, C13H13Br2NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Arbidol Impurity 46 (C13H13Br2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Arbidol Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13Br2NO3 |
| Molecular Weight | 391.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Arbidol Standards
- Arbidol Impurity 57 (CAS CATO-C4X-112957)
- Arbidol Impurity 21 (CAS 25900-97-4)
- Arbidol Impurity 15 (CAS CATO-C4X-112915)
- Arbidol Impurity 56 (CAS CATO-C4X-112956)
- Arbidol Impurity 29 (CAS CATO-C4X-112929)
- Arbidol Impurity 2 (CAS 131707-24-9)
- Arbidol Impurity 26 (CAS CATO-C4X-112926)
- Arbidol Impurity 82 (CAS 10588-31-5)
Recommended Standards
- Tert-butyl 5-bromo-3-(bromomethyl)-1H-pyrazolo[3,4-b]pyridine-1-carboxylate (CAS 916258-26-9)
- 4-Bromo-2,3-difluoro-6-iodo-1-(trimethylsilyl)benzene (CAS 1807646-35-0)
- 5,5''-Dibromo-2,2':6',2''-terpyridine (CAS 223463-10-3)
- 4-Bromo-N-(4-bromophenyl)benzenesulfonamide (CAS 100124-40-1)
- Cromoglicate EP Impurity B (CAS 16150-45-1)
- Fasudil Impurity 23 DiHCl (CAS 116700-36-8)
- Posaconazole Impurity 72 (CAS CATO-C4X-120872)
- N-(4-Fluoropyridin-2-yl)acetamide (CAS 1935912-75-6)
- tert-Butyl 3-{[(4-chlorophenyl)methyl]amino}-2-methylpropanoate (CAS 1221342-84-2)
- Fluorometholone Impurity 6 (CAS 110664-58-9)
- (R)-1-Cbz-3-methylpiperazine (CAS 623586-00-5)
- 3-(4-Bromophenyl)-5-methyl-1h-1,2,4-triazole (CAS 170230-86-1)
- Tert-butyl (R)-5-(trifluoromethyl)-1,4-diazepane-1-carboxylate (CAS 2381960-21-8)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com