Fluorometholone Impurity 6 CAS 110664-58-9
| CAS No. | 110664-58-9 |
| Molecular Formula | C22H29BrO4 |
| Molecular Weight | 437.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Fluorometholone Impurity 6 (CAS 110664-58-9), a pharmacopoeial impurity reference standard (molecular formula C22H29BrO4, MW 437.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution, Fluorometholone Impurity 6 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 437.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluorometholone Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H29BrO4 |
| Molecular Weight | 437.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
Related Fluorometholone Standards
- Fluorometholone Acetate (CAS 3801-06-7)
- Fluorometholone Impurity 11 (CAS CATO-C4X-193311)
- Fluorometholone Impurity 7 (CAS 2796-99-8)
- Fluorometholone Epoxy Analog (CAS 83873-17-0)
- Fluorometholone Impurity N12 (CAS 382-52-5)
- Fluorometholone Impurity 8 (CAS CATO-C4X-19338)
- Fluorometholone Impurity 2 (CAS 130145-14-1)
- Fluorometholone Acetate 6,9(11)-diene Impurity (CAS 95955-20-7)
Recommended Standards
- 5-(5-Bromo-1-ethyl-2-oxoindolin-3-ylidene)-3-cyclopentyl-2-thioxothiazolidin-4-one (CAS 617697-73-1)
- 4-((5-(Carboxymethyl)-2-hydroxyphenyl)diazenyl)phenyl (2-(trimethylammonio)ethyl) phosphate (CAS 359435-74-8)
- 3'-Bromo-10,10-dimethyl-Spiro[anthracene-9(10H),9'-[ 9H]fluorene] (CAS 2170533-42-1)
- 4-(2-(1-(3,4-Dichlorobenzyl)-1H-indol-3-yl)ethyl)thiomorpholine 1,1-dioxide (CAS 478047-25-5)
- Moxifloxacin Impurity 53 (CAS 151213-45-5（free base）)
- Nicardipine Impurity 62 (CAS CATO-C4X-171062)
- Lusutrombopag Impurity 84 (CAS CATO-C4X-208484)
- Methyl 2-amino-3-(3-cyanophenyl)propanoate hydrochloride (CAS 164648-62-8)
- H-Glu(OtBu)-Leu-OMe (hydrochloride) (CAS 85101-25-3)
- 2-Amino-3-(2,5-dioxopyrrolidin-1-yl)propanamide (CAS 1249592-06-0)
- Triethylamine Hydrochloride (CAS 554-68-7)
- 3-Amino-3-(3-thienyl)propanoic Acid (CAS 94333-62-7)
- 4-(5-amino-6-(1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)pyrazin-2-yl)-N-cyclopropyl-N-methylbenzenesulfonamide (CAS 1396771-17-7)
- Semaglutide238 (CAS CATO-C4X-2226238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com