3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile CAS 1492720-09-8
| CAS No. | 1492720-09-8 |
| Molecular Formula | C8H13N3O3S |
| Molecular Weight | 231.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile (CAS 1492720-09-8), a certified reference material (molecular formula C8H13N3O3S, MW 231.27 g/mol) for analytical method development and quality control.
The molecular framework of 3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile (C8H13N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H13N3O3S |
| Molecular Weight | 231.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- 1-(2-(2-(Dimethylamino)pyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352526-36-3)
- Methyl 1-(2-Methoxyethyl)-2-oxopyrrolidine-4-carboxylate (CAS 1272755-99-3)
- 1-(4-Chlorobenzylthio)acetone (CAS 40939-03-5)
- 2-(Benzyloxy)-5-chloro-3-nitrophenyl benzoate (CAS 891497-54-4)
- 6-benzyl-1,6-diazaspiro[3.4]octane (CAS 1158749-78-0)
- 3-(3-Bromophenyl)-1-methyl-1h-pyrazole-5-carboxylic acid (CAS 93618-35-0)
- (1-(Thiophen-2-ylmethyl)azetidin-3-yl)methanol (CAS 1484133-67-6)
- Peptide Impurity 82 (CAS 10491-78-8)
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