4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline CAS 149285-78-9
| CAS No. | 149285-78-9 |
| Molecular Formula | C9H8ClF3N2 |
| Molecular Weight | 236.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.62 g/mol gives 4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 149285-78-9) is a high-purity analytical reference standard with the molecular formula C9H8ClF3N2 and a molecular weight of 236.62 g/mol.
Based on its molecular formula C9H8ClF3N2, 4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF3N2 |
| Molecular Weight | 236.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-N-cyclopropyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1031619-96-1)
- 3-(3-Chloro-4-(trifluoromethyl)phenyl)propanal (CAS 1036396-40-3)
- 3-(2-Chloro-5-(trifluoromethyl)phenyl)propanal (CAS 1057670-86-6)
- 2-chloro-3-(4-(trifluoromethyl)phenyl)propanal (CAS 1149333-38-9)
- 4-Chloro-1-cyclopropoxy-2-(trifluoromethyl)benzene (CAS 1243313-35-0)
- 4-Chloro-2-cyclopropoxy-1-(trifluoromethyl)benzene (CAS 1243359-12-7)
- 1-Chloro-3-cyclopropoxy-5-(trifluoromethyl)benzene (CAS 1243360-23-7)
- 2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene (CAS 1243397-58-1)
Recommended Standards
- 2-(Allyloxy)-1-chloro-4-(trifluoromethyl)benzene (CAS 1443303-69-2)
- Ethyl 3-(chlorosulfonyl)-2,2-difluoropropanoate (CAS 1602961-92-1)
- 1-(4-Chloro-3-ethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1417517-71-5)
- 2-(Azetidin-3-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 1781241-45-9)
- 3-Bromo-N-(2-(ethylamino)-2-oxoethyl)thiophene-2-carboxamide (CAS 1211373-97-5)
- Aniline hydrobromide (CAS 542-11-0)
- 2,2,2-Trifluoroacetic acid compound with 7-azaspiro[3.5]nonane-2-carboxylic acid (1:1) (CAS 2173992-43-1)
- (S)-4-Phenethyloxazolidine-2,5-dione (CAS 1377983-54-4)
- 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2-[(2-fluorophenyl)methyl]-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775345-51-1)
- 2-Chloro-n-(pentan-3-yl)propanamide (CAS 1016888-28-0)
- 6-Bromo-5-fluoroisoquinolin-1(2H)-one (CAS 1445564-00-0)
- 7-Ethyl-1,2-dihydroisoquinolin-1-one (CAS 874532-26-0)
- 4-Bromo-2-(2-(4-methoxyphenyl)propan-2-yl)pyridine (CAS 1163707-63-8)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
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