5-bromo-4-fluoro-2-(4-methylpiperazin-1-yl)aniline CAS 1493046-77-7
| CAS No. | 1493046-77-7 |
| Molecular Formula | C11H15BrFN3 |
| Molecular Weight | 288.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-bromo-4-fluoro-2-(4-methylpiperazin-1-yl)aniline (CAS 1493046-77-7), molecular formula C11H15BrFN3 and molecular weight 288.16 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-bromo-4-fluoro-2-(4-methylpiperazin-1-yl)aniline (C11H15BrFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 288.16 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-bromo-4-fluoro-2-(4-methylpiperazin-1-yl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H15BrFN3 |
| Molecular Weight | 288.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related bromo Standards
- 2-bromo-N-[(2-fluorophenyl)methyl]-3-methylbutanamide (CAS 1016726-55-8)
- 1-(4-Bromo-2-fluorobenzyl)piperidin-4-ol (CAS 1044924-10-8)
- N-(3-bromo-4-fluorobenzyl)tetrahydro-2H-pyran-4-amine (CAS 1154882-81-1)
- N-(5-bromo-2-fluorobenzyl)tetrahydro-2H-pyran-4-amine (CAS 1155634-25-5)
- (1-(3-Bromo-4-fluorobenzyl)pyrrolidin-3-yl)methanol (CAS 1247368-14-4)
- 1-(5-Bromo-2-fluorobenzyl)piperidin-4-ol (CAS 1248251-53-7)
- 2-((2-Bromo-4-fluorophenoxy)methyl)piperidine (CAS 1251213-89-4)
- 3-Bromo-5-fluoro-N-[(oxan-4-yl)methyl]aniline (CAS 1269815-44-2)
Recommended Standards
- 3-(2-Bromo-5-fluorobenzyl)piperidin-3-ol (CAS 1490642-08-4)
- 4-(2-Bromo-4-fluorobenzyl)piperidin-4-ol (CAS 1498005-93-8)
- 3-(2-Bromo-4-fluorobenzyl)piperidin-3-ol (CAS 1479216-36-8)
- 4-(3-Bromo-5-fluorobenzyl)piperidin-4-ol (CAS 1504701-03-4)
- (R)-2-((1-Benzylpyrrolidin-3-yl)(ethyl)amino)ethanol (CAS 1353996-79-8)
- [(2-Chloro-4-Oxooxetan-2-Yl)Methyl]Pentafluorosulfur(VI) (CAS 70353-68-3)
- 1-({6-[(1-cyanocyclohexyl)amino]-hexyl}amino)cyclohexanecarbonitrile (CAS 22411-41-2)
- 7-Bromo-2-ethoxyquinoline (CAS 1223559-68-9)
- 5,5,5-Trifluoro-4,4-dihydroxypentanoic acid (CAS 45021-39-4)
- Irsogladine (CAS 57381-26-7)
- N-(4-hydroxyphenyl)dodecanamide (CAS 103-98-0)
- Azelastine Impurity 9 (CAS 19065-49-7)
- N-(benzyloxy)-4-nitrobenzene-1-sulfonamide (CAS 1033774-90-1)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com