4-(2-Bromo-4-fluorobenzyl)piperidin-4-ol CAS 1498005-93-8
| CAS No. | 1498005-93-8 |
| Molecular Formula | C12H15BrFNO |
| Molecular Weight | 288.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-Bromo-4-fluorobenzyl)piperidin-4-ol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(2-Bromo-4-fluorobenzyl)piperidin-4-ol (CAS 1498005-93-8), a certified reference material (molecular formula C12H15BrFNO, MW 288.16 g/mol) for analytical method development and quality control.
Structurally, 4-(2-Bromo-4-fluorobenzyl)piperidin-4-ol (C12H15BrFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 288.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15BrFNO |
| Molecular Weight | 288.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-bromo-N-[(2-fluorophenyl)methyl]-3-methylbutanamide (CAS 1016726-55-8)
- 1-(4-Bromo-2-fluorobenzyl)piperidin-4-ol (CAS 1044924-10-8)
- N-(3-bromo-4-fluorobenzyl)tetrahydro-2H-pyran-4-amine (CAS 1154882-81-1)
- N-(5-bromo-2-fluorobenzyl)tetrahydro-2H-pyran-4-amine (CAS 1155634-25-5)
- (1-(3-Bromo-4-fluorobenzyl)pyrrolidin-3-yl)methanol (CAS 1247368-14-4)
- 1-(5-Bromo-2-fluorobenzyl)piperidin-4-ol (CAS 1248251-53-7)
- 2-((2-Bromo-4-fluorophenoxy)methyl)piperidine (CAS 1251213-89-4)
- 3-Bromo-5-fluoro-N-[(oxan-4-yl)methyl]aniline (CAS 1269815-44-2)
Recommended Standards
- 5-bromo-4-fluoro-2-(4-methylpiperazin-1-yl)aniline (CAS 1493046-77-7)
- 4-(3-Bromo-5-fluorobenzyl)piperidin-4-ol (CAS 1504701-03-4)
- 3-(2-Bromo-5-fluorobenzyl)piperidin-3-ol (CAS 1490642-08-4)
- 1-(3-Bromo-5-fluorobenzyl)piperidin-4-ol (CAS 1514878-90-0)
- 4,5-Difluoro-1H-indole-2-carboxylic acid (CAS 884494-61-5)
- 4-(4-Fluorophenyl)-5-[(4-fluorophenyl)sulfanyl]-1,2,3-thiadiazole (CAS 338408-51-8)
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- Ethyl 3-(4-oxoquinazolin-3(4H)-yl)propanoate (CAS 173070-44-5)
- tert-butyl N-[(3S,4R)-3-hydroxytetrahydropyran-4-yl]carbamate (CAS 2408937-23-3)
- 2-(6-Amino-4-(difluoromethyl)-5-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806017-87-7)
- 5-amino-N-tert-butyl-1,3,4-thiadiazole-2-sulfonamide (CAS 1225484-47-8)
- 3,3,3-Trifluoropropane-1-sulfonyl Chloride (CAS 845866-80-0)
- 8-(2-Phenylethyl)-8-azabicyclo[3.2.1]octan-3-one (CAS 83507-66-8)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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