6-Iodo-5-(trifluoromethyl)nicotinamide CAS 1496535-11-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1496535-11-5
Molecular FormulaC7H4F3IN2O
Molecular Weight316.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Iodo-5-(trifluoromethyl)nicotinamide CAS 1496535-11-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Iodo-5-(trifluoromethyl)nicotinamide.

6-Iodo-5-(trifluoromethyl)nicotinamide (CAS 1496535-11-5) is a high-purity analytical reference standard with the molecular formula C7H4F3IN2O and a molecular weight of 316.02 g/mol.

6-Iodo-5-(trifluoromethyl)nicotinamide (C7H4F3IN2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Iodo-5-(trifluoromethyl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H4F3IN2O
Molecular Weight316.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF/I-containing
Nitrogen Atoms2

Related Iodo Standards

Recommended Standards

Why CATO?