3-Iodo-4-(trifluoromethoxy)benzaldehyde CAS 188725-98-6
| CAS No. | 188725-98-6 |
| Molecular Formula | C8H4F3IO2 |
| Molecular Weight | 316.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Iodo-4-(trifluoromethoxy)benzaldehyde.
3-Iodo-4-(trifluoromethoxy)benzaldehyde (CAS 188725-98-6) is a high-purity analytical reference standard with the molecular formula C8H4F3IO2 and a molecular weight of 316.02 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 3-Iodo-4-(trifluoromethoxy)benzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Iodo-4-(trifluoromethoxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F3IO2 |
| Molecular Weight | 316.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/I-containing |
Related Iodo Standards
- 3-Iodo-4-(trifluoromethyl)benzoic acid (CAS 1034690-61-3)
- 3-Iodo-2-(trifluoromethyl)benzoic acid (CAS 1261795-34-9)
- 6-Iodo-5-(trifluoromethyl)nicotinamide (CAS 1496535-11-5)
- 3-Iodo-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 1803834-29-8)
- 2-Iodo-3-(trifluoromethyl)benzoic acid (CAS 766473-89-6)
- 2-Iodo-4-(trifluoromethyl)benzoic Acid (CAS 54507-44-7)
- 2-Iodo-5-(trifluoromethyl)benzoic Acid (CAS 702641-04-1)
- 2-Iodo-6-(trifluoromethyl)benzoic acid (CAS 914637-39-1)
Recommended Standards
- 1,5,9,10-Tetrachloroanthracene (CAS 82843-47-8)
- 3-Iodo-5-(trifluoromethyl)benzoic acid (CAS 28186-62-1)
- 1,4,9,10-Tetrachloroanthracene (CAS 84655-45-8)
- 4,4'-(Bromomethylene)bis(chlorobenzene) (CAS 6306-46-3)
- 2-(3,5-Dichlorophenyl)butan-2-ol (CAS 76499-95-1)
- 2-(4-Methoxyphenoxy)-5-nitrobenzoic acid (CAS 33459-12-0)
- (1,3-Dithian-2-yl)triisopropylsilane (CAS 145251-89-4)
- 1-(2-Bromoethyl)pyrrolidine (CAS 54035-94-8)
- 1-Chloro-4-(4-pyridinylmethyl)phthalazine (CAS 101094-85-3)
- 1-(4-Hydroxypiperidin-1-yl)-2-(pyridin-4-ylthio)ethan-1-one (CAS 1156974-57-0)
- 2-(Chloromethyl)-6-cyano-3-(difluoromethyl)pyridine-5-acetic acid (CAS 1806848-88-3)
- 4-(2-Oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)butanoic acid (CAS 6646-65-7)
- Zn (CAS CATO-CCRM106034)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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