(R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine CAS 1496581-89-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1496581-89-5
Molecular FormulaC23H29F4N5
Molecular Weight451.50 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine CAS 1496581-89-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 451.50 g/mol gives (R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine (CAS 1496581-89-5), molecular formula C23H29F4N5 and molecular weight 451.50 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine (C23H29F4N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-4-(1-(2-Fluoroethyl)piperidin-4-yl)-6-(2-methylpyrrolidin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC23H29F4N5
Molecular Weight451.50 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms5

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