Amiodarone Impurity 35 CAS 149702-94-3
| CAS No. | 149702-94-3 |
| Molecular Formula | C20H18I2O3 |
| Molecular Weight | 560.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Amiodarone Impurity 35 (CAS 149702-94-3), a pharmacopoeial impurity reference standard (molecular formula C20H18I2O3, MW 560.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Amiodarone Impurity 35 (C20H18I2O3) contains a steroid core, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 560.16 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H18I2O3 |
| Molecular Weight | 560.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | I-containing |
Related Amiodarone Standards
- Amiodarone EP Impurity D (CAS 1951-26-4)
- Amiodarone Impurity I (CAS CATO-C4X-142515)
- Amiodarone Impurity 45 (CAS CATO-C4X-142545)
- Amiodarone Impurity 16 (CAS 1391054-75-3)
- Amiodarone Impurity 48 (CAS CATO-C4X-142548)
- Amiodarone Impurity 22 (CAS CATO-C4X-142522)
- Amiodarone Impurity 28 (CAS 318267-28-6)
- Amiodarone Impurity 29 (CAS CATO-C4X-142529)
Recommended Standards
- Z-Phe-Lys(Boc)-COCH2Cl (CAS 1456879-69-8)
- N,N'-[Bis(2,6-diMethylphenyl)-1,3-diMethyl-1,3-propanediylidene](Methyl) (triethylphosphine)palladiuM(II) (CAS 1224879-40-6)
- 503555-55-3 8-(5-Chloro-2-(4-methylpiperazin-1-yl)isonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide (CAS 503555-55-3)
- Macitentan Impurity 1 (CAS 441798-25-0)
- Minoxidil Impurity 70 (CAS CATO-C4X-170070)
- Tolvaptan Impurity 57 (CAS CATO-C4X-195557)
- Relebactam Impurity 147 (CAS CATO-C4X-2144147)
- 4-Iodo-5-methylisoxazole (CAS 7064-38-2)
- 4-Bromo-2-methylpentanenitrile (CAS 1467467-58-8)
- 3-(2-Chlorophenoxy)-2-(4-chlorophenyl)quinoline-4-carboxylic acid (CAS 477886-56-9)
- 1,1'-(Anthracene-1,5-diyl)diethanone (CAS 10210-34-1)
- Ethyl 5-ethyl-1,3,4-oxadiazole-2-carboxylate (CAS 37641-38-6)
- (S)-1-(3,4-Dichlorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212974-25-8)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
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