LCZ-696 Impurity 22 CAS 149709-59-1
| CAS No. | 149709-59-1 |
| Molecular Formula | C25H31NO4 |
| Molecular Weight | 409.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, LCZ-696 Impurity 22 (C25H31NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 409.52 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, LCZ-696 Impurity 22 (CAS 149709-59-1, C25H31NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), LCZ-696 Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31NO4 |
| Molecular Weight | 409.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-((dimethylamino)methyl)-1,5-di(naphthalen-1-yl)pentane-1,5-dione (CAS CATO-C4X-116758)
- LCZ-696 Impurity 79 (CAS CATO-C4X-169679)
- tert-butyl N-{3,5-dimethoxy-4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}carbamate (CAS 700804-54-2)
- LCZ-696 Impurity 82 (CAS 2131788-25-3)
- Tafluprost impurity 23 (CAS CATO-C4X-216323)
- Travoprost Impurity 39 (CAS CATO-C4X-192539)
- Fenoterol EP Impurity A HBr (CAS 38964-10-2)
- (6-Bromo-4-fluoropyridin-2-yl)methanamine (CAS 1393530-54-5)
- 5-Acetoxymethyl-2,3-dimethyl-4-nitropyridine-1-oxide (CAS 120003-74-9)
- Bisphenol F ethoxylate (2 EO/phenol) diacrylate (CAS 120750-67-6)
- Methyl 1,3-dioxoisoindoline-2-carboxylate (CAS 25543-10-6)
- Ethyl 3-(4-chlorophenyl)-3-methyloxirane-2-carboxylate (CAS 461437-55-8)
- 5-fluoro-3-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 2167069-02-3)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com