Tryptophan EP Impurity K CAS 149724-31-2
| CAS No. | 149724-31-2 |
| Molecular Formula | C20H19N3O2 |
| Molecular Weight | 333.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tryptophan EP Impurity K.
CATO supplies Tryptophan EP Impurity K (CAS 149724-31-2), a pharmacopoeial impurity reference standard (molecular formula C20H19N3O2, MW 333.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tryptophan EP Impurity K (C20H19N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 333.38 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tryptophan EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19N3O2 |
| Molecular Weight | 333.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
Related Tryptophan Standards
- Tryptophan EP Impurity L (CAS 287170-99-4)
- Tryptophan Impurity 9 (CAS 141215-69-2)
- Tryptophan Impurity 15 (CAS 180509-18-6)
- D-Tryptophan benzyl ester (CAS 141595-98-4)
- Tryptophan impurity 32 (CAS 2306500-74-1)
- Tryptophan Impurity 45 (CAS 2306500-72-9)
- Tryptophan Impurity 51 (CAS CATO-C4X-137351)
- Tryptophan Impurity 12 (CAS 56777-76-5)
Recommended Standards
- Nafamostat Impurity 44 (CAS CATO-C4X-133244)
- Imidafenacin Impurity 2 (CAS 503598-68-3)
- Dobutamine Impurity 37 (CAS CATO-C4X-129837)
- Bisacodyl Impurity 24 (CAS CATO-C4X-203724)
- Levodopa Impurity 8 (CAS 4790-08-3)
- Elobixibat Impurity 28 (CAS CATO-C4X-283828)
- Flomoxef Impurity 12 (CAS CATO-C4X-138212)
- 4,5-Dimethyl-2-pyrimidinol hydrochloride (CAS 92000-23-2)
- (5-(1H-1,2,4-Triazol-3-yl)tetrahydrofuran-2-yl)methanamine (CAS 1526342-93-7)
- 2,3-Anthracenedicarboxylic Anhydride (CAS 6812-14-2)
- 2-(Difluoromethylthio)bromobenzene (CAS 51679-54-0)
- 6-Methyltetrazolo[1,5-b]pyridazine (CAS 38693-80-0)
- 7-Benzothiazolamine (CAS 1123-55-3)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com