Tryptophan EP Impurity L CAS 287170-99-4
| CAS No. | 287170-99-4 |
| Molecular Formula | C21H19N3O2 |
| Molecular Weight | 345.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tryptophan EP Impurity L (CAS 287170-99-4) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19N3O2 and a molecular weight of 345.39 g/mol.
The molecular framework of Tryptophan EP Impurity L (C21H19N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Tryptophan EP Impurity L under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19N3O2 |
| Molecular Weight | 345.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Tryptophan Standards
- Tryptophan EP Impurity K (CAS 149724-31-2)
- Tryptophan Impurity 15 (CAS 180509-18-6)
- Tryptophan Impurity 9 (CAS 141215-69-2)
- Tryptophan impurity 42 (CAS CATO-C4X-137342)
- Tryptophan impurity 41 (CAS CATO-C4X-137341)
- Tryptophan EP Impurity J (CAS 164068-19-3)
- D-Tryptophan benzyl ester (CAS 141595-98-4)
- Tryptophan impurity 32 (CAS 2306500-74-1)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com