Posaconazole Impurity 6 CAS 149809-42-7
| CAS No. | 149809-42-7 |
| Molecular Formula | C21H21F2N3O4S |
| Molecular Weight | 449.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Posaconazole Impurity 6 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Posaconazole Impurity 6 (CAS 149809-42-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H21F2N3O4S and a molecular weight of 449.47 g/mol.
Based on its molecular formula C21H21F2N3O4S, Posaconazole Impurity 6 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 449.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21F2N3O4S |
| Molecular Weight | 449.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Posaconazole Standards
- Posaconazole Impurity 10 (CAS 149809-43-8)
- Posaconazole Impurity 11 (CAS 159811-30-0)
- Posaconazole Impurity 139 (CAS CATO-C4X-1208139)
- Posaconazole Impurity 140 (CAS CATO-C4X-1208140)
- Posaconazole Impurity 141 (CAS CATO-C4X-1208141)
- Posaconazole Impurity 142 (CAS CATO-C4X-1208142)
- Posaconazole Impurity 146 (CAS CATO-C4X-1208146)
- Posaconazole Impurity 147 (CAS CATO-C4X-1208147)
Recommended Standards
- Posaconazole Impurity 33 (CAS CATO-C4X-120833)
- Posaconazole Impurity 7 (CAS 166583-12-6)
- (11bR)-N-Methyl-N-[(R)-1-phenylethyl]-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 1021439-57-5)
- Ly309887 (CAS 127228-54-0)
- Valproate impurity 89 (CAS CATO-C4X-116689)
- Methotrexate Impurity 31 (CAS CATO-C4X-115431)
- Econazole EP Impurity B (CAS 2334059-11-7)
- 1-Benzyl 4-methyl 3-fluoropiperidine-1,4-dicarboxylate (CAS 1303972-82-8)
- 2-(3,3-Difluoropiperidin-1-yl)ethan-1-amine (CAS 1228631-24-0)
- NCC-149 (CAS 1316652-41-1)
- 1-(5-Bromo-2-hydroxyphenyl)-2-chloroethan-1-one (CAS 100959-21-5)
- 7-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 2061980-70-7)
- 2-(3-(Isopropylamino)propyl)isoindoline-1,3-dione (CAS 403998-13-0)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com