Posaconazole Impurity 139 CAS CATO-C4X-1208139
| CAS No. | CATO-C4X-1208139 |
| Molecular Formula | C21H21F2N3O4S |
| Molecular Weight | 449.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Posaconazole Impurity 139 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Posaconazole Impurity 139 (CAS CATO-C4X-1208139), a pharmacopoeial impurity reference standard (molecular formula C21H21F2N3O4S, MW 449.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Posaconazole Impurity 139 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H21F2N3O4S |
| Molecular Weight | 449.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Posaconazole Standards
- Posaconazole Impurity 10 (CAS 149809-43-8)
- Posaconazole Impurity 11 (CAS 159811-30-0)
- Posaconazole Impurity 140 (CAS CATO-C4X-1208140)
- Posaconazole Impurity 141 (CAS CATO-C4X-1208141)
- Posaconazole Impurity 142 (CAS CATO-C4X-1208142)
- Posaconazole Impurity 146 (CAS CATO-C4X-1208146)
- Posaconazole Impurity 147 (CAS CATO-C4X-1208147)
- Posaconazole Impurity 33 (CAS CATO-C4X-120833)
Recommended Standards
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
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- Tulathromycin A Impurity 8 (CAS 2051579-09-8)
- Clavulanic acid Impurity 18 (CAS 598-56-1)
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- α-Eudesmol (CAS 473-16-5)
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- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com