3-(2-Bromo-4-fluorophenyl)-2,2-dimethylpropan-1-ol CAS 1498180-19-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1498180-19-0
Molecular FormulaC11H14BrFO
Molecular Weight261.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2-Bromo-4-fluorophenyl)-2,2-dimethylpropan-1-ol CAS 1498180-19-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 261.13 g/mol gives 3-(2-Bromo-4-fluorophenyl)-2,2-dimethylpropan-1-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2-Bromo-4-fluorophenyl)-2,2-dimethylpropan-1-ol (CAS 1498180-19-0), molecular formula C11H14BrFO and molecular weight 261.13 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(2-Bromo-4-fluorophenyl)-2,2-dimethylpropan-1-ol (C11H14BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14BrFO
Molecular Weight261.13 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF/Br-containing

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