1-(3-Iodophenyl)pyrrolidine-2,4-dione CAS 1499167-19-9
| CAS No. | 1499167-19-9 |
| Molecular Formula | C10H8INO2 |
| Molecular Weight | 301.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(3-Iodophenyl)pyrrolidine-2,4-dione (CAS 1499167-19-9), a certified reference material (molecular formula C10H8INO2, MW 301.08 g/mol) for analytical method development and quality control.
1-(3-Iodophenyl)pyrrolidine-2,4-dione (C10H8INO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(3-Iodophenyl)pyrrolidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8INO2 |
| Molecular Weight | 301.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodophenyl Standards
- (5-(4-Iodophenyl)isoxazol-3-yl)methanol (CAS 1695039-91-8)
- 1-(3-Iodophenyl)pyrrolidine-2,5-dione (CAS 72601-46-8)
- 1-(2-Iodophenyl)piperidin-2-one (CAS 1033334-55-2)
- 1-[(4-Iodophenyl)carbonyl]pyrrolidine (CAS 168317-99-5)
- 1-(4-Iodophenyl)-3,3-dimethylazetidin-2-one (CAS 339100-84-4)
- 1-[(3-Iodophenyl)carbonyl]pyrrolidine (CAS 349118-15-6)
- N-(2-iodophenyl)cyclobutanecarboxamide (CAS 876536-89-9)
- N-(4-iodophenyl)-3-methylbut-2-enamide (CAS 634162-24-6)
Recommended Standards
- 2-((Fluoroiodomethyl)sulfonyl)pyridine (CAS 1415115-02-4)
- 3-Iodo-1-methyl-1H-indole-2-carboxylic acid (CAS 167631-59-6)
- 4-(3-iodopyrazol-1-yl)-2-methoxypyridine (CAS 1350475-30-7)
- 7-Iodo-6-methoxy-1,4-dihydroquinolin-4-one (CAS 1300031-68-8)
- 7-Nitro-1H-pyrrolo[3,2-b]pyridine (CAS 1190313-38-2)
- 2-(Tetrahydro-2H-pyran-2-ylmethoxy)-isonicotinonitrile (CAS 1016791-52-8)
- 2-[1-(5-bromo-2-methylphenyl)-n-methylformamido]acetic acid (CAS 1482137-44-9)
- 3-Amino-1-(piperidin-4-yl)urea dihydrochloride (CAS 1306603-58-6)
- 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde (CAS 227180-23-6)
- 3-((4-Chlorophenyl)amino)-1-phenyl-1H-pyrazol-5(4H)-one (CAS 7186-69-8)
- 5-Fluoro-3-(trifluoromethyl)pyridine-2-acetic acid (CAS 1214352-90-5)
- 2-Bromo-5-(difluoromethyl)pyridin-4-ol (CAS 1805314-69-5)
- 2,2'-[1,4-Phenylenebis(oxymethylene)]dioxirane (CAS 2425-01-6)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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