(2-Bromo-5-chlorophenyl)methanesulfonyl chloride CAS 1500851-58-0
| CAS No. | 1500851-58-0 |
| Molecular Formula | C7H5BrCl2O2S |
| Molecular Weight | 303.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2-Bromo-5-chlorophenyl)methanesulfonyl chloride (C7H5BrCl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (2-Bromo-5-chlorophenyl)methanesulfonyl chloride (CAS 1500851-58-0), a certified reference material (molecular formula C7H5BrCl2O2S, MW 303.99 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-Bromo-5-chlorophenyl)methanesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrCl2O2S |
| Molecular Weight | 303.99 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-3-chloro-2-methylbenzenesulfonyl chloride (CAS 1208075-53-9)
- 4-Bromo-2-chloro-6-methylbenzenesulfonyl chloride (CAS 1208076-76-9)
- 4-Bromo-5-chloro-2-methylbenzene-1-sulfonyl chloride (CAS 1208076-84-9)
- 4-Bromo-2-chloro-5-methylbenzenesulfonyl chloride (CAS 1246776-80-6)
- 3-Bromo-2-chloro-5-methylbenzenesulfonyl chloride (CAS 1263376-78-8)
- 4-Bromo-3-chloro-5-methylbenzenesulfonyl chloride (CAS 1349715-49-6)
- 5-bromo-4-chloro-2-methylbenzene-1-sulfonyl chloride (CAS 1416349-30-8)
- 1-Bromo-5-fluoro-4-nitro-2-(trifluoromethoxy)benzene (CAS 1417568-44-5)
Recommended Standards
- 4-Bromo-3-fluoro-6-nitro-2-(trifluoromethyl)phenol (CAS 1445995-81-2)
- (2-Bromo-3-chlorophenyl)methanesulfonyl chloride (CAS 1536276-49-9)
- (2-Bromo-4-chlorophenyl)methanesulfonyl Chloride (CAS 1427379-23-4)
- 1-Bromo-2-fluoro-4-nitro-5-(trifluoromethoxy)benzene (CAS 1805938-98-0)
- 4-(cyanomethyl)oxane-4-carbonitrile (CAS 194862-82-3)
- 4-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-α-[4-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)phenyl]-α-methylbenzenemethanol (CAS 1639063-72-1)
- Olaparib Impurity 64 (CAS 155295-47-9)
- Boc-D-Orn(Z)-OH (CAS 16937-92-1)
- (R)-1-(3-Chlorophenyl)ethanamine hydrochloride (CAS 1167414-90-5)
- (3,6-Dichloropyridazin-4-yl)methanamine (CAS 871014-15-2)
- 1-((2-Ethylhexyl)amino)-4-(methylamino)anthracene-9,10-dione (CAS 75476-94-7)
- 3,5-Dichlorobenzo[b]thiophene-2-carbaldehyde (CAS 1095081-89-2)
- 2-Cyclopropyl-4,6-dimethylpyrimidine-5-carboxylic acid (CAS 548773-17-7)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
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