Gefitinib Impurity 1 CAS 1502829-45-9
| CAS No. | 1502829-45-9 |
| Molecular Formula | C29H37ClFN5O4 |
| Molecular Weight | 574.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Gefitinib Impurity 1 (CAS 1502829-45-9), a pharmacopoeial impurity reference standard (molecular formula C29H37ClFN5O4, MW 574.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C29H37ClFN5O4, Gefitinib Impurity 1 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 574.09 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Gefitinib Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H37ClFN5O4 |
| Molecular Weight | 574.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Gefitinib Standards
- Gefitinib Impurity 84 (CAS CATO-C4X-111784)
- Gefitinib impurity 65 (CAS CATO-C4X-111765)
- Gefitinib Impurity 95 (CAS CATO-C4X-111795)
- Gefitinib Impurity 31 (CAS CATO-C4X-111731)
- Gefitinib Impurity 96 (CAS CATO-C4X-111796)
- Gefitinib Impurity 52 (CAS CATO-C4X-111752)
- Gefitinib Impurity 17 (CAS CATO-C4X-111717)
- Gefitinib Impurity 4 (CAS 2089650-13-3)
Recommended Standards
- Chlorotricarbonyl(4,4'-di-t-butyl-2,2'-bipyridine)rhenium(I) (CAS 165612-19-1)
- Chloro{N-[(1R,2R)-2-[(S)-[2-[[1,2,3,4,5,6-η)-4-methylphenyl]methoxy]ethyl]amino]-1,2-diphenylethylmethanesulfonamidato}ruthenium(II) (CAS 1333981-86-4)
- NS 5806 (CAS 426834-69-7)
- Chloro{N-[(1S,2S)-2-[(R)-[2-[[1,2,3,4,5,6-η)-4-methylphenyl]methoxy]ethyl]amino]-1,2-diphenylethylmethanesulfonamidato}ruthenium(II) (CAS 1361318-83-3)
- Ticagrelor Impurity 155 (CAS 1482484-62-7)
- Saxagliptin Impurity 46 (CAS 361440-67-7)
- Lasmiditan Impurity 63 (CAS CATO-C4X-247863)
- rel-(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate (CAS 252873-35-1)
- 2-Bromo-6-chloro-3-(trifluoromethyl)acetophenone (CAS 1805018-17-0)
- 1H-pyrazolo[3,4-b]pyridin-6-ol (CAS 61514-61-2)
- 6-(Boc-aminomethyl)-3-azabicyclo[3.1.1]heptane (CAS 1363382-87-9)
- N3-(2,4-dichlorobenzyl)-N3-propyl-6-chloro-4-(trifluoromethyl)nicotinamide (CAS 680213-98-3)
- (R)-N-(3-Methyl-1-(pyrrolidin-1-yl)butan-2-yl)-P,P-diphenylphosphinic amide (CAS 2643943-04-6)
- Uremic Pentapeptide (CAS 71494-20-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com