Gefitinib Impurity 4 CAS 2089650-13-3
| CAS No. | 2089650-13-3 |
| Molecular Formula | C22H24Cl2N4O3 |
| Molecular Weight | 463.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Gefitinib Impurity 4 (CAS 2089650-13-3, C22H24Cl2N4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H24Cl2N4O3, Gefitinib Impurity 4 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 463.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Gefitinib Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24Cl2N4O3 |
| Molecular Weight | 463.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Gefitinib Standards
Recommended Standards
- Clevidipine-d7 (CAS CATO-C4X-101523)
- Budesonide Impurity 61 (CAS 131711-17-6)
- 2-({4-[(2,4-dichlorophenoxy)methyl]-2-nitrophenyl}sulfanyl)-1,3-benzothiazole (CAS 477869-58-2)
- Trazodone Impurity 84 (CAS CATO-C4X-177284)
- Spermine Impurity 1 (CAS CATO-C4X-33931)
- Olmesartan Impurity 36 (CAS 1092980-84-1)
- Aceclofenac Impurity 15 (CAS CATO-C4X-153115)
- N-(2,6-Dichloro-4-pyridyl)-N'-phenylurea (CAS 75279-45-7)
- Vadimezan (CAS 117570-53-3)
- (2-Aminobenzo[d]oxazol-4-yl)methanol (CAS 1806379-16-7)
- Propionylcarnitine (CAS 17298-37-2)
- 4-BRomo-N-(4-fluoro-2-methylphenyl)benzenesulfonamide (CAS 899228-13-8)
- 2-Methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1693-94-3)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com