Sivelestat sodium Impurity 2 CAS 150374-99-5
| CAS No. | 150374-99-5 |
| Molecular Formula | C11H13ClO4S |
| Molecular Weight | 276.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sivelestat sodium Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Sivelestat sodium Impurity 2 (CAS 150374-99-5) is a certified pharmaceutical impurity reference standard with the molecular formula C11H13ClO4S and a molecular weight of 276.74 g/mol.
Sivelestat sodium Impurity 2 (C11H13ClO4S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H13ClO4S |
| Molecular Weight | 276.74 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Sivelestat Standards
- Sivelestat sodium Impurity 32 (CAS CATO-C4X-212332)
- Sivelestat sodium impurity 41 (CAS CATO-C4X-212341)
- Sivelestat sodium impurity 42 (CAS CATO-C4X-212342)
- Sivelestat sodium impurity 43 (CAS CATO-C4X-212343)
- Sivelestat Impurity 10 (CAS CATO-C4X-212310)
- Sivelestat Impurity 27 (CAS CATO-C4X-212327)
- Sivelestat sodium impurity 45 (CAS CATO-C4X-212345)
- Sivelestat Impurity 18 (CAS 150374-97-3)
Recommended Standards
- 5-Chloro-N,3-dimethyl-2-(methylsulfonamido)benzamide (CAS 2831004-03-4)
- Oxolan-2-ylmethyl 4-chlorobenzene-1-sulfonate (CAS 929971-67-5)
- N-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylene](3-pyridinyl)methanamine (CAS 241132-70-7)
- Methyl 2-[4-(chlorosulfonyl)phenyl]-2-methylpropanoate (CAS 612532-24-8)
- Hyoscyamine Impurity 3 (CAS CATO-C4X-34373)
- Thiotepa Impurity 8 (CAS CATO-C4X-21568)
- Ampicillin Impurity 19 (CAS CATO-C4X-144319)
- 2-((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)ethene-1,1,2-tricarbonitrile (CAS 324040-58-6)
- D-N-Benzylserine Methyl Ester (CAS 131110-76-4)
- 1-(Pyrazin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1103848-03-8)
- 2-(2,4,6-Tribromophenoxy)ethyl acrylate (CAS 7347-19-5)
- Etrasimod Impurity 35 (CAS CATO-C4X-321435)
- 2-(But-3-yn-1-yl)-5,5-dimethyl-1,2,4-oxadiazolidin-3-one (CAS 728948-80-9)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com