Sivelestat Impurity 27 CAS CATO-C4X-212327
| CAS No. | CATO-C4X-212327 |
| Molecular Formula | C12H16O5S |
| Molecular Weight | 272.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sivelestat Impurity 27 is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Sivelestat Impurity 27 (CAS CATO-C4X-212327, C12H16O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H16O5S, Sivelestat Impurity 27 contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sivelestat Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16O5S |
| Molecular Weight | 272.32 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 1 |
Related Sivelestat Standards
- Sivelestat sodium Impurity 2 (CAS 150374-99-5)
- Sivelestat sodium Impurity 32 (CAS CATO-C4X-212332)
- Sivelestat sodium impurity 41 (CAS CATO-C4X-212341)
- Sivelestat sodium impurity 42 (CAS CATO-C4X-212342)
- Sivelestat sodium impurity 43 (CAS CATO-C4X-212343)
- Sivelestat Impurity 10 (CAS CATO-C4X-212310)
- Sivelestat sodium impurity 45 (CAS CATO-C4X-212345)
- Sivelestat Impurity 18 (CAS 150374-97-3)
Recommended Standards
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- Rimegepant Impurity 83 (CAS CATO-C4X-248783)
- Imipenem Impurity 3 (CAS 104154-92-9)
- Rimegepant Impurity 85 (CAS CATO-C4X-248785)
- Amorolfine EP Impurity D HCl (CAS 67306-03-0（free base）)
- Benzyl Alcohol Impurity 8 (CAS 30640-46-1)
- Rizatriptan EP Impurity C (CAS 208941-96-2)
- 1-(2-Methoxyethyl)piperidine-4-carbaldehyde (CAS 342435-23-8)
- (4-Methylnaphthalen-1-yl)hydrazine (CAS 210696-77-8)
- Cyclohexyl(2,4-difluorophenyl)methanol (CAS 1249419-53-1)
- 3-Chloro-4-(pyridin-2-ylmethoxy)benzoic acid (CAS 1304082-42-5)
- 4-[(2-Methyl-1H-benzimidazol-1-yl)methyl]-benzoic acid hydrochloride (CAS 907948-02-1)
- 2-(2-Thienyl)benzaldehyde (CAS 99902-07-5)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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