5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-g]isoquinoline Hydrochloride CAS 15052-05-8
| CAS No. | 15052-05-8 |
| Molecular Formula | C10H11NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-g]isoquinoline Hydrochloride (CAS 15052-05-8) is a high-purity analytical reference standard with the molecular formula C10H11NO2HCl and a molecular weight of 213.66 g/mol.
The molecular framework of 5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-g]isoquinoline Hydrochloride (C10H11NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-g]isoquinoline Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11NO2 HCl |
| Molecular Weight | 213.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-((((3AR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)methyl)benzonitrile (CAS 1134156-51-6)
- 6-Ethyl-2-(5-methylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 588711-29-9)
- Ethyl(E)-7-chlorohept-2-enoate (CAS 107408-35-5)
- 3,5-Difluoro-4-(1h-pyrazol-1-yl)benzaldehyde (CAS 1342028-33-4)
- Barium nitrate (CAS 10022-31-8)
- 3-(3-Cyanophenyl)propanoic Acid (CAS 42287-97-8)
- 9H-Purine-6-sulfonyl fluoride (CAS 1513-63-9)
- (2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 2549171-72-2)
- N-(2-Chloroethyl)-2-propanamine Hydrochloride (CAS 6306-61-2)
- Bax inhibitor peptide V5 (CAS 579492-81-2)
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