4-((4-(Trifluoromethyl)pyridin-2-yl)thio)pyridin-3-amine CAS 1505372-23-5
| CAS No. | 1505372-23-5 |
| Molecular Formula | C11H8F3N3S |
| Molecular Weight | 271.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 271.26 g/mol gives 4-((4-(Trifluoromethyl)pyridin-2-yl)thio)pyridin-3-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-((4-(Trifluoromethyl)pyridin-2-yl)thio)pyridin-3-amine (CAS 1505372-23-5), molecular formula C11H8F3N3S and molecular weight 271.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((4-(Trifluoromethyl)pyridin-2-yl)thio)pyridin-3-amine (C11H8F3N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-((4-(Trifluoromethyl)pyridin-2-yl)thio)pyridin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8F3N3S |
| Molecular Weight | 271.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 1-[2-(2-Trifluoromethyl-phenyl)-thiazol-4-yl]-ethanone (CAS 1469150-14-8)
- 1-[2-(3-Trifluoromethyl-phenyl)-thiazol-4-yl]-ethanone (CAS 1487901-79-0)
- 4-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)pyrimidine-2-thiol (CAS 1858250-86-8)
- 1-(2-(4-(Trifluoromethyl)phenyl)thiazol-4-yl)ethan-1-one (CAS 263564-37-0)
- 2-((4-(Trifluoromethyl)pyrimidin-2-yl)thio)aniline (CAS 680593-98-0)
- N-(4-(trifluoromethyl)phenyl)thiophene-3-carboxamide (CAS 201354-23-6)
- 4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehyde 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde 438577-61-8 (CAS 438577-61-8)
- 2-(5-(4-(Trifluoromethyl)phenyl)furan-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 730958-61-9)
Recommended Standards
- tert-Butyl (E)-3-[6-(difluoromethoxy)pyridin-3-yl]prop-2-enoate (CAS 1621614-95-6)
- Benzyl 3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 174073-95-1)
- Benzyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate (CAS 1334417-91-2)
- 8-methyl-8-azabicyclo[3.2.1]oct-2-en-3-yl trifluoromethanesulfonate (CAS 183810-37-9)
- (4-Formylpiperazinyl)-N-((4-methylphenyl)sulfonyl)formamide (CAS 1023870-84-9)
- tert-Butyl (3S,4S)-3-ethoxy-4-hydroxypyrrolidine-1-carboxylate (CAS 2325666-09-7)
- 2-(Difluoromethoxy)quinoline (CAS 2341-27-7)
- Tert-butyl (S)-3-(acetamidomethyl)pyrrolidine-1-carboxylate (CAS 1482515-22-9)
- N-(3-aminopropyl)-N-methylmethanesulfonamide hydrochloride (CAS 1955554-00-3)
- 2-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)acetic Acid (CAS 134997-91-4)
- 6-(1-Methylhydrazinyl)pyrimidin-4(1H)-one (CAS 94295-29-1)
- 8-methanesulfonylquinoline (CAS 5825-42-3)
- (2R,3R,4R,5R)-4-(((2S,3R,4S,5S,6R)-6-(azidomethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal (CAS 1499187-31-3)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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