Topiramate Chlorosulfonyl Impurity CAS 150609-95-3
| CAS No. | 150609-95-3 |
| Molecular Formula | C12H19ClO8S |
| Molecular Weight | 358.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Topiramate Chlorosulfonyl Impurity (C12H19ClO8S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Topiramate Chlorosulfonyl Impurity (CAS 150609-95-3), a pharmacopoeial impurity reference standard (molecular formula C12H19ClO8S, MW 358.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Topiramate Chlorosulfonyl Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19ClO8S |
| Molecular Weight | 358.79 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Topiramate Standards
- Topiramate Impurity 30 (CAS CATO-C4X-176830)
- Topiramate Impurity 27 (CAS 120238-48-4)
- Topiramate Impurity 17 (CAS 97240-80-7)
- Topiramate Azidosulfate (CAS 106881-35-0)
- Topiramate-d12 (CAS 1279037-95-4)
- Topiramate Impurity 21 (CAS CATO-C4X-176821)
- Topiramate Impurity 28 (CAS 53209-16-8)
- Topiramate Impurity 34 (CAS CATO-C4X-176834)
Recommended Standards
- 7-((4-Chlorobenzyl)thio)-2-(furan-2-yl)pyrazolo[1,5-d][1,2,4]triazin-4(5H)-one (CAS 1040683-72-4)
- Ethyl 2-((4-(4-chlorophenyl)-6-(difluoromethyl)pyrimidin-2-yl)thio)acetate (CAS 938020-64-5)
- (R)-(+)-DBD-Pro-COCl [=(R)-(+)-4-(N,N-Dimethylaminosulfonyl)-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 150993-62-7)
- 3-[(2-Chloro-6-fluorophenyl)methyl]-4-hydroxy-1-[2-(pyridin-2-yl)ethyl]-1,2-dihydropyridin-2-one (CAS 477860-56-3)
- Dorzagliatin Impurity 20 (CAS CATO-C4X-344120)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
- Tiamulin impurity 21 (CAS CATO-C4X-221021)
- 2-Methyl-4-(morpholin-4-yl)butan-2-amine (CAS 1263002-61-4)
- 1-methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine dihydrochloride (CAS 485402-33-3)
- (4-Chloro-2-fluorobenzyl)(phenyl)sulfane (CAS 1443344-76-0)
- 3-((4-Chlorophenyl)thio)pentane-2,4-dione (CAS 132787-93-0)
- (S)-Quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride hydrate (CAS 312695-48-0)
- Imipenem EP Impurity B (CAS 1197869-90-1)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
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