Topiramate Impurity 27 CAS 120238-48-4
| CAS No. | 120238-48-4 |
| Molecular Formula | C13H22O9S |
| Molecular Weight | 354.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Topiramate Impurity 27 (CAS 120238-48-4) is a certified pharmaceutical impurity reference standard with the molecular formula C13H22O9S and a molecular weight of 354.37 g/mol.
Based on its molecular formula C13H22O9S, Topiramate Impurity 27 contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 354.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H22O9S |
| Molecular Weight | 354.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Sulfur Atoms | 1 |
Related Topiramate Standards
- Topiramate Impurity 17 (CAS 97240-80-7)
- Topiramate-d12 (CAS 1279037-95-4)
- Topiramate Impurity 30 (CAS CATO-C4X-176830)
- Topiramate Chlorosulfonyl Impurity (CAS 150609-95-3)
- Topiramate-<SUP>13</SUP>C<SUB>6</SUB> (CAS 1217455-55-4)
- Topiramate Azidosulfate (CAS 106881-35-0)
- Topiramate Impurity 21 (CAS CATO-C4X-176821)
- Topiramate Impurity 36 (CAS 455899-78-2)
Recommended Standards
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