Methyl 5-bromo-4-fluoro-2-iodobenzoate CAS 1509204-33-4
| CAS No. | 1509204-33-4 |
| Molecular Formula | C8H5BrFIO2 |
| Molecular Weight | 358.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 5-bromo-4-fluoro-2-iodobenzoate (C8H5BrFIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Methyl 5-bromo-4-fluoro-2-iodobenzoate (CAS 1509204-33-4) is a high-purity analytical reference standard with the molecular formula C8H5BrFIO2 and a molecular weight of 358.93 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrFIO2 |
| Molecular Weight | 358.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br/I-containing |
Related Methyl Standards
- Methyl 3-bromo-5-fluoro-4-iodobenzoate (CAS 1160574-64-0)
- Methyl 2-bromo-5-fluoro-3-iodobenzoate (CAS 1499694-56-2)
- Methyl 5-bromo-2-fluoro-3-iodobenzoate (CAS 1510575-52-6)
- Methyl 4-bromo-5-fluoro-2-iodobenzoate (CAS 1864354-56-2)
- Methyl 4-bromo-2-fluoro-6-iodobenzoate (CAS 1935413-12-9)
- Methyl 3-bromo-2-fluoro-6-iodobenzoate (CAS 1936253-89-2)
- 3-Bromo-5-fluoro-6-iodo-2-methylbenzoic acid (CAS 2725767-16-6)
- Methyl 2-bromo-6-fluoro-3-iodobenzoate (CAS 2383683-94-9)
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- [D-Ser8]-Semaglutide A (CAS CATO-C4X-2226116)
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