2-Amino-4-(trifluoromethyl)thiazole-5-carbonitrile CAS 151729-42-9
| CAS No. | 151729-42-9 |
| Molecular Formula | C5H2F3N3S |
| Molecular Weight | 193.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-4-(trifluoromethyl)thiazole-5-carbonitrile (CAS 151729-42-9) is a high-purity analytical reference standard with the molecular formula C5H2F3N3S and a molecular weight of 193.15 g/mol.
Based on its molecular formula C5H2F3N3S, 2-Amino-4-(trifluoromethyl)thiazole-5-carbonitrile contains a nitrile group, sulfur-containing functionality, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 193.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H2F3N3S |
| Molecular Weight | 193.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 5-Amino-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile (CAS 1094619-79-0)
- 4-Amino-2-methoxy-5-nitrobenzonitrile (CAS 1196074-43-7)
- 7-Amino-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1211486-58-6)
- 2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 124738-80-3)
- 2-amino-4-methoxy-5-nitrobenzonitrile (CAS 1269292-82-1)
- Methyl 6-amino-1H-purine-2-carboxylate (CAS 130413-38-6)
- Methyl 5-amino-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate (CAS 1352504-79-0)
- 2-Amino-7-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1394306-55-8)
Recommended Standards
- 2-(Cyanomethyl)-4,5-difluorobenzimidazole (CAS 1500714-70-4)
- 2-(Cyanomethyl)-5,7-difluorobenzimidazole (CAS 1533815-59-6)
- 1H-Benzimidazole-2-carbonitrile, 6,7-difluoro-1-methyl- (CAS 1499108-26-7)
- β-D-Glucopyranuronosylamine (CAS 163659-65-2)
- 5-(6-Chloropyridin-3-yl)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 306936-75-4)
- 2-(Benzylthio)-1-(4-fluorophenyl)-5-(p-tolyl)-1H-imidazole (CAS 1207009-05-9)
- 4-Bromo-8-chloroquinoline 927800-40-6 C9H5BrClN V9207 (CAS 927800-40-6)
- Isobutyltriphenylphosphonium Bromide (CAS 22884-29-3)
- Ethyl 2-[bis(2-naphthalenyloxy)phosphinyl]acetate (CAS 188945-33-7)
- 289-56-5 3-methyl-5-(methylsulfanyl)-2,4-dihydro-7h-pyrazolo[4,3-d]pyrimidin-7-one AR-1F4319 (CAS 289-56-5)
- N-(2-Methoxybenzyl)-1-(2-(pyrrolidin-1-yl)pyrimidin-5-yl)methanamine (CAS 1279216-96-4)
- 4-Bromo-2-chloro-1-(3-chloropropoxy)benzene (CAS 1040050-91-6)
- 3-(2-Methoxy-5-methylphenyl)pentan-3-ol (CAS 1338982-31-2)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com