2-Chlorothiazolo[4,5-b]pyridine CAS 152170-30-4
| CAS No. | 152170-30-4 |
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chlorothiazolo[4,5-b]pyridine.
CATO supplies 2-Chlorothiazolo[4,5-b]pyridine (CAS 152170-30-4), a certified reference material (molecular formula C6H3ClN2S, MW 170.62 g/mol) for analytical method development and quality control.
2-Chlorothiazolo[4,5-b]pyridine (C6H3ClN2S) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorothiazolo Standards
- 2-Chlorothiazolo[5,4-c]pyridine (CAS 1190927-31-1)
- 6-Chlorothiazolo[4,5-c]pyridine (CAS 1206982-73-1)
- 5-Chlorothiazolo[5,4-b]pyridine (CAS 1313726-12-3)
- 7-Chlorothiazolo[5,4-b]pyridine (CAS 1427501-90-3)
- 7-Chlorothiazolo[4,5-b]pyridine (CAS 1556129-57-7)
- 2-Chlorothiazolo[4,5-c]pyridine (CAS 884860-63-3)
- 2-Chlorothiazolo[5,4-b]pyridine (CAS 91524-96-8)
- 4-Chlorothiazolo[4,5-c]pyridine (CAS 214045-74-6)
Recommended Standards
- Tizanidine Impurity 50 (CAS CATO-C4X-144550)
- 5-Chlorobenzo-2,1,3-thiadiazole (CAS 2207-32-1)
- 1-methylpyrazole-4-sulfonyl chloride 288148-34-5 4-(Chlorosulphonyl)-1-methyl-1H-pyrazole (CAS 288148-34-5)
- 3-Chloropropiophenone(2-d2) (CAS 34236-34-5)
- Piperidin-2-yl(pyrrolidin-1-yl)methanone (CAS 130605-98-0)
- 7-Methoxy-3-nitro-1H-pyrrolo[2,3-c]pyridine (CAS 1190314-26-1)
- 4-Amino-3-cyano-6-(trifluoromethoxy)pyridine-2-sulfonyl chloride (CAS 1806183-99-2)
- 2-(2,4-Difluorophenyl)-2-methylpropanoic acid (CAS 920501-67-3)
- (4-Fluoro-3-propoxyphenyl)(methyl)sulfane (CAS 1379292-31-5)
- 1-(Chloromethyl)-2-methoxy-benzene (CAS 7035-02-1)
- 2-(chloromethyl)-5-phenyl-1,3-thiazole (CAS 859470-58-9)
- Ethyl 4,4-dibromo-2,2-dimethyl-3-oxobutanoate (CAS 151556-85-3)
- 1-[4-(2,2,2-trifluoroethoxy)phenyl]ethan-1-amine (CAS 942938-39-8)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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