4-(Chloromethoxy)-1,2-difluorobenzene CAS 1521891-48-4
| CAS No. | 1521891-48-4 |
| Molecular Formula | C7H5ClF2O |
| Molecular Weight | 178.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(Chloromethoxy)-1,2-difluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(Chloromethoxy)-1,2-difluorobenzene (CAS 1521891-48-4) is a high-purity analytical reference standard with the molecular formula C7H5ClF2O and a molecular weight of 178.56 g/mol.
4-(Chloromethoxy)-1,2-difluorobenzene (C7H5ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2O |
| Molecular Weight | 178.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloromethoxy Standards
- 1-(Chloromethoxy)-2,4-difluorobenzene (CAS 1531521-64-8)
- 2-(Chloromethoxy)-1,4-difluorobenzene (CAS 1542044-70-1)
- 1-(chloromethoxy)octane 24566-90-3 Chloromethyl octyl ether (CAS 24566-90-3)
- 3-(Chloromethoxy)-1,1,2,2-tetrafluoropropane (CAS 848337-76-8)
- 1-(chloromethoxy)-1H-benzo[d][1,2,3]triazole (CAS 3912-23-0)
- 1,3-Bis(chloromethoxy)propane (CAS 138418-40-3)
- 1-(Chloromethoxy)-4-methoxybenzene (CAS 35657-08-0)
- 1-(3-(Chloromethoxy)phenyl)ethan-1-one (CAS 1502858-14-1)
Recommended Standards
- 4-Chloro-3,5-difluorobenzenemethanol (CAS 1431329-58-6)
- 1-Chloro-3,4-difluoro-2-methoxybenzene (CAS 1373921-04-0)
- (2-Chloro-4,6-difluorophenyl)methanol (CAS 1534389-83-7)
- 1-Chloro-2,5-difluoro-4-methoxybenzene (CAS 1261846-22-3)
- (4-Chloro-6-methoxypyridin-2-yl)methanamine (CAS 1060810-39-0)
- N-Boc-2-(tosyloxymethyl)morpholine (CAS 130546-33-7)
- N-{9-acetyl-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-13-yl}-2-chlorobenzene-1-sulfonamide (CAS 866157-27-9)
- Ethyl 3-cyclopentyl-1-methyl-1H-pyrazole-5-carboxylate (CAS 1033443-99-0)
- 1-Benzoyl-3-(2-hydroxyphenyl)thiourea (CAS 53514-41-3)
- 5-(2,3,4-Trimethoxyphenyl)cyclohexane-1,3-dione (CAS 119101-24-5)
- 4-Chloro-3-phenoxypyridine (CAS 73406-90-3)
- 4-(Azetidin-1-ylmethyl)benzonitrile (CAS 1851533-63-5)
- 5-(Aminomethyl)-5-methyl-2,4-imidazolidinedione (CAS 86970-24-3)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com