1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanamine CAS 1522407-49-3
| CAS No. | 1522407-49-3 |
| Molecular Formula | C13H13F6N |
| Molecular Weight | 297.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanamine (CAS 1522407-49-3), a certified reference material (molecular formula C13H13F6N, MW 297.24 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13F6N |
| Molecular Weight | 297.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 3-(3,5-Bis(trifluoromethyl)phenyl)piperidine (CAS 1187228-26-7)
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclobutanemethanamine (CAS 1504202-93-0)
- 2-[2-(trifluoromethyl)benzenesulfonamido]propanoic acid (CAS 1008938-50-8)
- (2S)-2-[2-(Trifluoromethyl)benzenesulfonamido]propanoic acid (CAS 1212137-65-9)
- Methyl 6-(3-(trifluoromethyl)phenoxy)picolinate (CAS 136227-55-9)
- 5-Benzyl-3-(trifluoromethyl)-1H,3aH,6aH-pyrrolo[3,4-c]pyrazole-4,6-dione (CAS 1428147-22-1)
- 2-Methyl-5-((4-(trifluoromethyl)pyrimidin-2-yl)amino)benzoic acid (CAS 1495407-96-9)
- 2-((2-Oxo-4-(trifluoromethyl)-2h-chromen-7-yl)methyl)acrylamide (CAS 480438-95-7)
Recommended Standards
- 8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 1794818-27-1)
- 1-Benzyl-3,3-bis(trifluoromethyl)pyrrolidine (CAS 1315368-00-3)
- (+/-)-Boc-alpha-phosphonoglycine Trimethyl Ester (CAS 89524-98-1)
- 8-[3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 1239728-35-8)
- Bis [Acetyl 2-[(2-Formamide-1,6-dihydro-6-chloro-9H-purin-9yl)methoxy]ethyl Ester] (CAS 1346600-44-9)
- 2-(2-Fluorophenyl)hydrazine-1-carbothioamide (CAS 446275-93-0)
- 5-Acetyl-6,7-dihydrobenzo[b]thiophen-4(5h)-one (CAS 19983-48-3)
- 8-bromo-7-methyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine (CAS 2414185-23-0)
- Tri-o-tolylphosphine tetrafluoroborate (CAS 1255640-57-3)
- 1-(1H-benzo[d]imidazol-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1017666-26-0)
- (3-((Tetrahydrofuran-3-yl)oxy)pyridin-4-yl)methanamine (CAS 1507096-98-1)
- Macluraxanthone (CAS 5848-14-6)
- Nandrolone Cycloate (CAS 22263-51-0)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
Why CATO?
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