8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one CAS 1794818-27-1
| CAS No. | 1794818-27-1 |
| Molecular Formula | C14H8FN5O2 |
| Molecular Weight | 297.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.24 g/mol gives 8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 1794818-27-1), molecular formula C14H8FN5O2 and molecular weight 297.24 g/mol, is a CATO reference standard with documented purity and traceability.
8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one (C14H8FN5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8FN5O2 |
| Molecular Weight | 297.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fluorophenyl Standards
- 8-[3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 1239728-35-8)
- 2-[(4-Fluorophenyl)sulfanyl]-5-(trifluoromethyl)benzonitrile (CAS 477866-78-7)
- Methyl 2-(4-fluorophenyl)-5-phenyloxazole-4-carboxylate (CAS 1427954-46-8)
- Methyl 5-(4-fluorophenyl)-2-phenyloxazole-4-carboxylate (CAS 1427954-81-1)
- 2-(3-Fluorophenyl)-2'-oxospiro[cyclopropane-1,3'-indoline]-5'-carboxylic acid (CAS 1707405-58-0)
- 2-(4-Fluorophenyl)-2'-oxospiro[cyclopropane-1,3'-indoline]-5'-carboxylic acid (CAS 1708269-21-9)
- 3-(4-Fluorophenyl)-N-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 339021-32-8)
- Methyl 2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylate (CAS 339106-79-5)
Recommended Standards
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanamine (CAS 1522407-49-3)
- (+/-)-Boc-alpha-phosphonoglycine Trimethyl Ester (CAS 89524-98-1)
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclobutanemethanamine (CAS 1504202-93-0)
- 1-(3-Cyano-4-fluorophenyl)-5-(furan-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 503614-46-8)
- N-methoxy-N-methylpyrimidine-5-carboxamide (CAS 823189-68-0)
- tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate (CAS 1935172-10-3)
- (1S,2S)-2-(2-(9H-xanthen-9-yl)acetyl)cyclopropanecarboxylic acid (CAS 203208-44-0)
- 2-[(5-Amino-2-pyridinyl)(ethyl)amino]-1-ethanol (CAS 1017221-30-5)
- Ethyl 5-formyl-1-methyl-1H-imidazole-4-carboxylate (CAS 2106384-57-8)
- 5-(2-Methanesulfinylphenyl)-3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 339099-83-1)
- [1-(4-methoxyphenyl)pyrrolidin-3-yl]methanol (CAS 1017445-06-5)
- 3-Bromo-4-methylbenzylamine (CAS 1177558-32-5)
- 3-Methyl-5,7-bis(methylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 62871-65-2)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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