Chlorhexidine EP Impurity N CAS 152504-10-4
| CAS No. | 152504-10-4 |
| Molecular Formula | C15H25ClN8 |
| Molecular Weight | 352.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Chlorhexidine EP Impurity N is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Chlorhexidine EP Impurity N (CAS 152504-10-4, C15H25ClN8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Chlorhexidine EP Impurity N (C15H25ClN8) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H25ClN8 |
| Molecular Weight | 352.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Chlorhexidine Standards
- Chlorhexidine Impurity 19 (CAS CATO-C4X-225619)
- Chlorhexidine Impurity 25 (CAS CATO-C4X-225625)
- Chlorhexidine Impurity 32 (CAS CATO-C4X-225632)
- Chlorhexidine Digluconate Solution EP Impurity L (CAS CATO-C4X-225637)
- Chlorhexidine Impurity 5 (CAS 2518301-34-1)
- Chlorhexidine EP Impurity A (CAS 152504-08-0)
- Chlorhexidine Diacetate EP Impurity B (CAS 1308292-89-8)
- Chlorhexidine Impurity 31 (CAS CATO-C4X-225631)
Recommended Standards
- (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2-(4-chloro-3-fluorophenyl)cyclopropanecarboxylate (CAS 1799381-70-6)
- Di-1-adamantylphosphinic chloride, 98% (CAS 126683-99-6)
- Desloratadine Impurity 9 (CAS 117796-52-8)
- 4-Bromo-5-iodo-6-(trifluoromethyl)pyrimidine (CAS 1706458-44-7)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
- Indometacin Impurity 54 (CAS CATO-C4X-147054)
- Mianserin Impurity 74 (CAS CATO-C4X-136974)
- O-Benzyl-α-N-tert-Boc-L-serinehydroxamic Acid (CAS 26048-92-0)
- N1,N1-Bis(2-(phenylthio)ethyl)oxalamide (CAS 191980-39-9)
- 2-((2-Aminoethyl)(methyl)amino)-1-(thiophen-2-yl)ethanone (CAS 1353943-78-8)
- 4-Ethylbenzamide (CAS 33695-58-8)
- (1S,2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-((R)-1-hydroxypropyl)cyclopent-3-ene-1,2-diol (CAS 194353-48-5)
- 2-(1H-Imidazol-1-ylmethyl)cyclopentanone (CAS 116802-67-6)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com