Chlorhexidine Diacetate EP Impurity B CAS 1308292-89-8
| CAS No. | 1308292-89-8 |
| Molecular Formula | C16H26ClN9O |
| Molecular Weight | 395.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Chlorhexidine Diacetate EP Impurity B (CAS 1308292-89-8), a pharmacopoeial impurity reference standard (molecular formula C16H26ClN9O, MW 395.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Chlorhexidine Diacetate EP Impurity B (C16H26ClN9O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 395.89 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H26ClN9O |
| Molecular Weight | 395.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Chlorhexidine Standards
- Chlorhexidine EP Impurity A (CAS 152504-08-0)
- Chlorhexidine Impurity 19 (CAS CATO-C4X-225619)
- Chlorhexidine Impurity 18 (CAS CATO-C4X-225618)
- Chlorhexidine EP Impurity N (CAS 152504-10-4)
- Chlorhexidine Impurity 25 (CAS CATO-C4X-225625)
- Chlorhexidine Impurity 32 (CAS CATO-C4X-225632)
- Chlorhexidine Digluconate Solution EP Impurity L (CAS CATO-C4X-225637)
- Chlorhexidine Impurity 5 (CAS 2518301-34-1)
Recommended Standards
- 2-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one (CAS 860649-48-5)
- 1-Bromo-4-iodo-5-nitro-2-(trifluoromethyl)benzene (CAS 1187385-82-5)
- (1-(3-Chloro-4-methylphenyl)-1H-1,2,3-triazol-4-yl)(4-(4-methylpiperazin-1-yl)phenyl)methanone (CAS 477847-90-8)
- 2,4,6-Tris(3,5-dimethylphenyl)-1,3,5,2,4,6-trioxatriborinane (CAS 34907-38-5)
- Fosaprepitant Impurity 21 (CAS 265121-01-5)
- Glycopyrronium Bromide EP Impurity D (CAS 65-85-0)
- Ondansetron Impurity 14 (CAS 30354-18-8)
- 1-(2-Chlorophenyl)-3-((2-methoxyadamantan-2-yl)methyl)urea (CAS 1797025-91-2)
- (2-Fluoro-6-(piperidin-4-yl)pyridin-4-yl)boronic acid (CAS 2225180-45-8)
- 4-Fluorobenzothioamide (CAS 22179-72-2)
- 8-Nitro-3,7-dihydro-1H-purine-2,6-dione (CAS 80106-09-8)
- (2,4-Dichlorophenyl)(thieno[2,3-b]quinolin-2-yl)methanone (CAS 478260-42-3)
- (2,3-Dichloro-6-fluorophenyl)boronic acid (CAS 1451393-17-1)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com