Methyl 4-bromo-2-chloro-5-iodobenzoate CAS 1529124-65-9
| CAS No. | 1529124-65-9 |
| Molecular Formula | C8H5BrClIO2 |
| Molecular Weight | 375.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 4-bromo-2-chloro-5-iodobenzoate (CAS 1529124-65-9), molecular formula C8H5BrClIO2 and molecular weight 375.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 4-bromo-2-chloro-5-iodobenzoate (C8H5BrClIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClIO2 |
| Molecular Weight | 375.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br/I-containing |
Related Methyl Standards
- Methyl 3-bromo-5-chloro-4-iodobenzoate (CAS 1160574-80-0)
- Methyl 2-bromo-4-chloro-5-iodobenzoate (CAS 1208077-68-2)
- Methyl 5-bromo-4-chloro-2-iodobenzoate (CAS 1528948-34-6)
- Methyl 3-bromo-2-chloro-5-iodobenzoate (CAS 1566999-42-5)
- Methyl 2-bromo-3-chloro-5-iodobenzoate (CAS 2383015-21-0)
- Methyl 3-bromo-5-chloro-2-iodobenzoate (CAS 933585-60-5)
- Methyl 5-bromo-2-chloro-3-iodobenzoate (CAS 933672-38-9)
- 6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 731827-26-2)
Recommended Standards
- 3-tert-butyl 5-methyl 7-fluoro-4,4-dimethyl-4H,5H-imidazo[1,5-a]quinoxaline-3,5-dicarboxylate (CAS 148858-31-5)
- 7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-77-5)
- Sinensetin-d3 (CAS 1438399-79-1)
- 2-Amino-4-bromo-3-chloro-5-iodobenzamide (CAS 2803280-68-2)
- 4’-Methoxy-3’,5’-dimethylacetophenone (CAS 60609-65-6)
- 2-Methoxy-6-methylnicotinamide (CAS 72918-09-3)
- 2-Methyl-1-((5-(trifluoromethyl)pyridin-2-yl)oxy)propan-2-amine (CAS 1340191-15-2)
- N-(1-Cyanocyclohexyl)-2-((4-ethoxyphenyl)amino)propanamide (CAS 1009269-51-5)
- methyl 4-butoxy-2-chlorobenzoate (CAS 1803583-66-5)
- 2-[benzyl(carboxymethyl)amino]acetic acid hydrochloride (CAS 1803582-94-6)
- 5-(Chloromethyl)-2-phenyl-1H-1,2,4-triazol-3(2H)-one (CAS 42284-57-1)
- 1-Methyl-4-((6-methylpyridin-3-yl)methyl)piperazine (CAS 1245646-56-3)
- benzyl (2-cyanopropan-2-yl)carbamate (CAS 100134-82-5)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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