6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one CAS 731827-26-2

Purity 97%+In StockPharmaceutical Standards
CAS No.731827-26-2
Molecular FormulaC16H27BrN2OS
Molecular Weight375.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one CAS 731827-26-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one.

6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 731827-26-2) is a high-purity analytical reference standard with the molecular formula C16H27BrN2OS and a molecular weight of 375.37 g/mol.

The molecular framework of 6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (C16H27BrN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-bromo-3-(1-phenylethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H27BrN2OS
Molecular Weight375.37 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentBr-containing
Nitrogen Atoms2
Sulfur Atoms1

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