3-Chloro-4-((trimethylsilyl)ethynyl)aniline CAS 1533424-84-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-4-((trimethylsilyl)ethynyl)aniline.

3-Chloro-4-((trimethylsilyl)ethynyl)aniline (CAS 1533424-84-8) is a high-purity analytical reference standard with the molecular formula C11H14ClNSi and a molecular weight of 223.77 g/mol.

The molecular framework of 3-Chloro-4-((trimethylsilyl)ethynyl)aniline (C11H14ClNSi) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Chloro-4-((trimethylsilyl)ethynyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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