Flupentixol Impurity 1 CAS 1535-17-7
| CAS No. | 1535-17-7 |
| Molecular Formula | C24H30N2O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Flupentixol Impurity 1 (CAS 1535-17-7, C24H30N2O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Flupentixol Impurity 1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 447.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Flupentixol Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H30N2O2S 2*HCl |
| Molecular Weight | 447.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Flupentixol Standards
- Flupentixol Impurity 21 (CAS 107265-28-1)
- Flupentixol Impurity 22 (CAS 129722-10-7)
- Flupentixol Impurity 20 (CAS 1581762-35-7)
- Flupentixol Dihydrochloride EP Impurity G (CAS 1693-28-3)
- Flupentixol Impurity N96 (CAS 2244985-34-8)
- Flupentixol EP Impurity A Enantiomer (CAS 2340-57-0)
- Flupentixol EP Impurity A (CAS 23904-98-5)
- Flupentixol DiHCl (CAS 2413-38-9)
Recommended Standards
- Vildagliptin Impurity 69 (CAS CATO-C4X-110069)
- Carbasalate EP Impurity A (CAS 1466-82-6)
- Perindopril Impurity 25 HCl (CAS 130982-52-4)
- 1,3-Thiazol-4-ylmethanesulfonyl chloride (CAS 754966-95-5)
- (R)-Benzyl 3-((2-aminoethyl)(methyl)amino)pyrrolidine-1-carboxylate (CAS 1354009-59-8)
- 2-Methyl-3-(oxazol-2-yl)aniline (CAS 1251266-25-7)
- 2-(3-Chloropropanesulfonyl)-1,3-benzothiazole (CAS 2602-79-1)
- (3S,4S)-4-aminotetrahydro-2H-pyran-3-carboxylic acid hydrochloride (CAS 2306249-66-9)
- 3-Methyl-N-pentylbenzamide (CAS 330466-41-6)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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