Arbidol Impurity 3 CAS 153633-10-4
| CAS No. | 153633-10-4 |
| Molecular Formula | C22H24Br2N2O3S |
| Molecular Weight | 556.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 556.31 g/mol gives Arbidol Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Arbidol Impurity 3 (CAS 153633-10-4) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24Br2N2O3S and a molecular weight of 556.31 g/mol.
The molecular framework of Arbidol Impurity 3 (C22H24Br2N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Arbidol Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24Br2N2O3S |
| Molecular Weight | 556.31 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Arbidol Standards
- Arbidol Impurity 50 (CAS 1312943-27-3)
- Arbidol Impurity 8 (CAS 1312943-26-2)
- Arbidol Sulfone (CAS 151455-32-2)
- Arbidol Impurity 36 (CAS CATO-C4X-112936)
- Arbidol Impurity 9 (CAS CATO-C4X-11299)
- Arbidol Sulfoxide (CAS 151455-33-3)
- Arbidol Impurity 20 (CAS CATO-C4X-112920)
- Arbidol Impurity 30 (CAS CATO-C4X-112930)
Recommended Standards
- (Z)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enamido)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide (CAS CATO-C4X-218054)
- ethyl 5-cyano-6-{[2-({[(2,6-dichloro-4-pyridyl)amino]carbonyl}amino)phenyl]thio}-2-(trifluoromethyl)nicotinate (CAS 266362-81-6)
- Fluralaner Impurity 15 (CAS 1805814-99-6)
- 1-(3-(1H-Imidazol-4-yl)propyl)-3-(3-((5-bromopyridin-2-yl)(3,4-dichlorobenzyl)amino)propyl)thiourea (CAS 199522-35-5)
- Landiolol Impurity 14 (CAS 154467-16-0)
- Olopatadine lmpurity 60 (CAS CATO-C4X-171861)
- Difelikefalin Impurity 86 (CAS CATO-C4X-304186)
- 1-(4-Aminophenyl)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one (CAS 1184563-60-7)
- Ethyl 4-(2-(benzo[d]oxazol-2-ylthio)acetamido)benzoate (CAS 58915-09-6)
- 9-Methylacridine-4-carboxylic acid (CAS 89459-36-9)
- N-(4-Phenoxyphenyl)-1,3-benzothiazol-2-amine (CAS 380346-15-6)
- 4-bromo-N-(2H-indazol-6-yl)-3-methoxybenzene-1-sulfonamide (CAS 727420-58-8)
- 4,5,6,7-Tetrahydro-2-benzofuran-1-carboxylic acid (CAS 1378818-17-7)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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