1-(4-Bromo-2-fluorophenyl)dihydropyrimidine-2,4(1H,3H)-dione CAS 1537382-63-0
| CAS No. | 1537382-63-0 |
| Molecular Formula | C10H8BrFN2O2 |
| Molecular Weight | 287.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Bromo-2-fluorophenyl)dihydropyrimidine-2,4(1H,3H)-dione.
1-(4-Bromo-2-fluorophenyl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 1537382-63-0) is a high-purity analytical reference standard with the molecular formula C10H8BrFN2O2 and a molecular weight of 287.09 g/mol.
1-(4-Bromo-2-fluorophenyl)dihydropyrimidine-2,4(1H,3H)-dione (C10H8BrFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Bromo-2-fluorophenyl)dihydropyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8BrFN2O2 |
| Molecular Weight | 287.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 5-(2-Bromo-4-fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 1251925-16-2)
- Ethyl 6-bromo-8-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1260763-32-3)
- 5-(5-Bromo-2-fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 1266784-17-1)
- 6-Bromo-1-ethyl-7-fluoro-4H-quinoxaline-2,3-dione (CAS 1400644-97-4)
- Ethyl 8-bromo-6-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1421312-22-2)
- Ethyl 3-bromo-6-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1427460-92-1)
- Ethyl 5-bromo-4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1443538-39-3)
- 1-(4-bromo-3-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 1515197-90-6)
Recommended Standards
- Ethyl 5-bromo-6-fluoro-1h-1,3-benzodiazole-2-carboxylate (CAS 1528623-85-9)
- 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine (CAS 1612287-99-6)
- (2-(4-Methylpiperidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1704063-77-3)
- (2-Fluoro-3-((4-methylbenzyl)carbamoyl)phenyl)boronic acid (CAS 1449145-04-3)
- 4-(3-(2,4-Dimethylphenyl)-3-oxoprop-1-en-1-yl)phenyl thiophene-2-carboxylate (CAS 331460-50-5)
- 3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444156-88-1)
- L-Leucine allyl ester-4-toluenesulfonate salt (CAS 88224-03-7)
- 4-(2-Bromoacetyl)-2-chloro-benzonitrile (CAS 182626-08-0)
- N-(4-Aminophenyl)-2-(4-chlorophenoxy)acetamide (CAS 953717-19-6)
- 2-Methylimidazo[1,2-a]pyridine-3,8-diol (CAS 769090-82-6)
- 2-Acetyl-5-methyloxazole-4-carboxamide (CAS 61183-14-0)
- 5-Bromo-2-chloro-1,8-naphthyridine (CAS 1260880-09-8)
- 3-(5-(Hydroxymethyl)pyridin-3-yl)benzonitrile (CAS 887973-94-6)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com