3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide CAS 444156-88-1
| CAS No. | 444156-88-1 |
| Molecular Formula | C28H21Cl2N3OS |
| Molecular Weight | 518.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (C28H21Cl2N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444156-88-1) is a high-purity analytical reference standard with the molecular formula C28H21Cl2N3OS and a molecular weight of 518.46 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H21Cl2N3OS |
| Molecular Weight | 518.46 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 6-Acetyl-3-amino-N-(4-(trifluoromethoxy)phenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 704876-21-1)
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Recommended Standards
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(2,4-dimethylphenyl)acetamide (CAS 332177-22-7)
- CiceritolDISCONTINUED (CAS 88167-26-4)
- 1-((5-Bromo-2-(trifluoromethoxy)phenyl)sulfonyl)-4-((tert-butyldimethylsilyl)oxy)piperidine (CAS 1704065-48-4)
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- 4,6-Dimethyl-1H-pyrazolo[4,3-c]pyridine (CAS 154390-78-0)
- 2-Bromo-4-trifluoromethylphenylisothiocyanate (CAS 688763-22-6)
- 2-Iodo-4-nitrobenzonitrile (CAS 300627-43-4)
- 4-Bromo-6-(difluoromethyl)-3-methylpyridin-2-ol (CAS 1805366-92-0)
- 1-(4-Chloro-2-fluorobenzyl)-1h-pyrazol-4-amine (CAS 1240565-79-0)
- 2-Ethynyl-N-methylbenzamide (CAS 139334-73-9)
- Methyl 3-(pyrimidin-5-yl)acrylate (CAS 224776-14-1)
- Acetyl decapeptide-3 (CAS 935288-50-9)
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