4-[(4-amino-3-fluorophenyl)methyl]-1-methylpiperazin-2-one CAS 1539447-43-2
| CAS No. | 1539447-43-2 |
| Molecular Formula | C12H16FN3O |
| Molecular Weight | 237.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(4-amino-3-fluorophenyl)methyl]-1-methylpiperazin-2-one.
CATO supplies 4-[(4-amino-3-fluorophenyl)methyl]-1-methylpiperazin-2-one (CAS 1539447-43-2), a certified reference material (molecular formula C12H16FN3O, MW 237.27 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(4-amino-3-fluorophenyl)methyl]-1-methylpiperazin-2-one (C12H16FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[(4-amino-3-fluorophenyl)methyl]-1-methylpiperazin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16FN3O |
| Molecular Weight | 237.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related amino Standards
- Methyl 2-amino-4-(5-methylfuran-2-yl)thiophene-3-carboxylate (CAS 1019521-41-5)
- (5-Amino-2-fluorophenyl)(4-methylpiperazin-1-yl)methanone (CAS 1156817-81-0)
- 2-Amino-3-(benzo[b]thiophen-3-yl)-3-hydroxypropanoic acid (CAS 1464778-80-0)
- Methyl 3-amino-6-methoxybenzo[b]thiophene-2-carboxylate (CAS 189439-55-2)
- 2-Amino-1-(4-(2-fluorophenyl)piperazin-1-yl)ethan-1-one (CAS 938338-02-4)
- Ethyl 2-amino-4-(furan-2-yl)thiophene-3-carboxylate (CAS 256506-99-7)
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Recommended Standards
- (3-(Aminomethyl)piperidin-1-yl)(3-fluoropyridin-4-yl)methanone (CAS 1479261-12-5)
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- Methyl 4-(3-fluorophenyl)-1-methylpyrrolidine-3-carboxylate (CAS 1706442-20-7)
- 2-(3-Aminopyrrolidin-1-yl)-N-(2-fluorophenyl)acetamide (CAS 1458143-20-8)
- N4-isopropyl-5-nitro-N4,N6-diphenylpyrimidine-4,6-diamine (CAS 866009-80-5)
- 1-[2-Amino-5-chloro-4-(triisopropylsilyloxy)phenyl]-2,2,2-trifluoroethanone 1-[2-Amino-5-chloro-4-[[tris(1-methylethyl)silyl]oxy]phenyl]-2,2,2-trifluoroethanone 2-Trifluoroacetyl-4-chloro-5-triisopropylsilyloxyaniline 342621-21-0 (CAS 342621-21-0)
- tert-butyl 4-{2-oxo-octahydro-1H-imidazolidino[4,5-c]pyridin-1-yl}piperidine-1-carboxylate (CAS 1909310-15-1)
- 3-Amino-4H-thieno[3,4-c]chromen-4-one (CAS 41078-15-3)
- 2,3-Dihydrobenzofuran-6-carbonitrile (CAS 1112184-64-1)
- 3-(2-Methylphenyl)but-2-enoic acid, mixture of isomers (CAS 1807940-69-7)
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- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
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