3-(Trifluoromethyl)piperazin-2-one CAS 1540402-18-3
| CAS No. | 1540402-18-3 |
| Molecular Formula | C5H7F3N2O |
| Molecular Weight | 168.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Trifluoromethyl)piperazin-2-one is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(Trifluoromethyl)piperazin-2-one (CAS 1540402-18-3), a certified reference material (molecular formula C5H7F3N2O, MW 168.12 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-(Trifluoromethyl)piperazin-2-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7F3N2O |
| Molecular Weight | 168.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1001020-14-9)
- 4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde (CAS 102808-02-6)
- 4-(Trifluoromethyl)pyrimidin-2-ol (CAS 104048-92-2)
- 3-(trifluoromethyl)-1H-pyrazin-2-one (CAS 1191035-90-1)
- 6-(Trifluoromethyl)tetrahydropyridazin-3(2H)-one (CAS 1216205-41-2)
- 5-(trifluoromethyl)-1H-pyrazin-2-one (CAS 134510-03-5)
- 2-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 1546-80-1)
- 1-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1556454-55-7)
Recommended Standards
- 1-(3-Aminoazetidin-1-yl)-2,2,2-trifluoroethan-1-one (CAS 1478086-61-1)
- 1-trifluoroacetimidazole (CAS 1546-79-8)
- 2-Fluoro-6-formylbenzoic acid (CAS 1289266-50-7)
- 3-(2,2,2-trifluoroethyl)imidazolidin-4-one (CAS 1549264-32-5)
- 1-Allyl-5-amino-4-methylpyridin-2(1h)-one (CAS 1505424-98-5)
- 2-(Ethylamino)propan-1-ol (CAS 24417-04-7)
- Diisobutylaluminum hydride solution (CAS 1191-15-7)
- 5,6-Dichloro-2,4-pyrimidinediamine (CAS 89033-89-6)
- 11,11-Difluoro-8-azadispiro[3.0.55.14]undecane hydrochloride (CAS 2098076-75-4)
- 3-(((4-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477855-78-0)
- 5-Bromo-4-methyl-2-(methylthio)pyrimidine (CAS 1294446-69-7)
- 1-Oxaspiro[4.5]dec-2-en-4-one (CAS 76951-95-6)
- 4-{2-[2-(tert-Butyl)-4-chlorophenoxy]-ethyl}piperidine hydrochloride (CAS 1220030-83-0)
- Insulin B (22-25) (CAS 34367-73-2)
Why CATO?
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