5,6-Dichloro-2,4-pyrimidinediamine CAS 89033-89-6
| CAS No. | 89033-89-6 |
| Molecular Formula | C4H4Cl2N4 |
| Molecular Weight | 179.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,6-Dichloro-2,4-pyrimidinediamine (CAS 89033-89-6) is a high-purity analytical reference standard with the molecular formula C4H4Cl2N4 and a molecular weight of 179.01 g/mol.
The molecular framework of 5,6-Dichloro-2,4-pyrimidinediamine (C4H4Cl2N4) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,6-Dichloro-2,4-pyrimidinediamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4Cl2N4 |
| Molecular Weight | 179.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloro Standards
- 2,5-Dichloro-4,6-pyrimidinediamine (CAS 13117-14-1)
- 4,6-Dichloro-2-hydrazinylpyrimidine (CAS 887592-69-0)
- 4,6-Dichloro-N-methyl-1,3,5-triazin-2-amine (CAS 27282-80-0)
- 5,6-Dichloro-1-methylpyrimidin-4(1H)-one (CAS 101912-72-5)
- 4,6-Dichloro-2-methoxypyrimidine (CAS 1074-40-4)
- 4,6-Dichloro-3-methoxypyridazine (CAS 112342-58-2)
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- 2,4-Dichloro-1-methyl-1H-imidazole-5-carbaldehyde (CAS 1240526-82-2)
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