5-Fluoro-2-oxo-2H-chromene-3-carboxylic acid CAS 1540476-86-5
| CAS No. | 1540476-86-5 |
| Molecular Formula | C10H5FO4 |
| Molecular Weight | 208.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoro-2-oxo-2H-chromene-3-carboxylic acid (C10H5FO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Fluoro-2-oxo-2H-chromene-3-carboxylic acid (CAS 1540476-86-5), molecular formula C10H5FO4 and molecular weight 208.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-2-oxo-2H-chromene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5FO4 |
| Molecular Weight | 208.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 7-Fluoro-2-oxo-2H-chromene-3-carboxylic acid (CAS 1353870-09-3)
- 8-Fluoro-2-oxo-2H-chromene-4-carboxylic acid (CAS 1355181-58-6)
- 6-Fluoro-2-oxo-2H-chromene-4-carboxylic acid (CAS 1355219-85-0)
- 6-Fluoro-2,3-dihydroxynaphthalene-1,4-dione (CAS 89226-84-6)
- 6-Fluoro-2-oxo-2h-chromene-3-carboxylic acid (CAS 937688-27-2)
- 6-Fluoro-4-oxo-4H-chromene-3-carboxylic acid (CAS 71346-17-3)
- 8-Fluoro-2-oxo-2H-chromene-3-carboxylic acid (CAS 625823-51-0)
- 8-Fluoro-4-oxo-4H-chromene-2-carboxylic acid (CAS 93340-04-6)
Recommended Standards
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- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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